Recombinant Human ACSM4 Protein, MYC/DDK-tagged
Cat.No. : | ACSM4-1024H |
Product Overview : | Recombinant human ACSM4 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
Molecular Mass : | 65.5 kDa |
Purity : | >50 ug/mL as determined by microplate BCA method |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | ACSM4 acyl-CoA synthetase medium-chain family member 4 [ Homo sapiens ] |
Official Symbol : | ACSM4 |
Synonyms : | acyl-CoA synthetase medium-chain family member 4 |
Gene ID : | 341392 |
mRNA Refseq : | NM_001080454 |
Protein Refseq : | NP_001073923 |
MIM : | 614360 |
UniProt ID : | P0C7M7 |
Products Types
◆ Recombinant Protein | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionACSM4 has been shown to interact with FABP and ABCA1, among other lipid metabolism-related proteins, and may play a role in regulating the transport and metabolism of fatty acids in cells.
ACSM4 has a unique substrate specificity compared to other members of the acyl-CoA synthetase family, preferring long-chain fatty acids with unsaturated bonds.
ACSM4 has been shown to interact with other proteins involved in lipid droplet formation and turnover, such as perilipin and adipose triglyceride lipase (ATGL), and may play a role in promoting the breakdown and utilization of stored lipids.
The regulation of ACSM4 expression is not well understood, but it may be influenced by dietary factors and metabolic status.
ACSM4 has been shown to regulate autophagy, a process by which cells break down and recycle damaged or unnecessary cellular components. Specifically, ACSM4 has been shown to promote the clearance of damaged mitochondria via autophagy in some cell types.
ACSM4 is expressed in a variety of tissues, including the liver, kidney, heart, and skeletal muscle.
ACSM4 has been shown to be a downstream target of AMPK, a key regulator of cellular energy metabolism. AMPK activation can lead to increased ACSM4 expression and activity, which may help cells better respond to metabolic stress.
ACSM4 is thought to play a role in promoting lipid uptake and oxidation in skeletal muscle cells, which can help improve insulin sensitivity and glucose metabolism.
ACSM4 has been implicated in the regulation of inflammation in various tissues. It may play a role in modulating the production of inflammatory cytokines and other mediators.
Studies have suggested that ACSM4 expression may be upregulated in insulin-resistant states, such as obesity and type 2 diabetes. The exact mechanism by which ACSM4 contributes to insulin resistance is not well understood.
Customer Reviews (5)
Write a reviewIts exceptional characteristics and superior performance have greatly enhanced the accuracy and validity of our findings.
Using this protein is like having a cup of coffee with your favorite lab mate. It's comforting, reliable, and gives you that extra boost in your research!
Simplified workflows, increased experimental efficiency.
Quality product, reasonable pricing, and exceptional service. A winning combination.
This protein has proven to be an invaluable asset in our laboratory.
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