ACSM4
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Official Full Name
acyl-CoA synthetase medium-chain family member 4
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Synonyms
ACSM4; acyl-CoA synthetase medium-chain family member 4; acyl-coenzyme A synthetase ACSM4, mitochondrial; similar to olfactory specific medium chain acyl CoA synthetase;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.Coli or Yeast
- HEK293
- HEK293T
- Mammalian Cell
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | ACSM4-3136H | Recombinant Human ACSM4, His-tagged | E.Coli or Yeast | His | 580 | |
Human | ACSM4-1024H | Recombinant Human ACSM4 Protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Mouse | ACSM4-1233M | Recombinant Mouse ACSM4 Protein | Mammalian Cell | His | ||
Mouse | Acsm4-1511M | Recombinant Mouse Acsm4 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Mouse | ACSM4-277M | Recombinant Mouse ACSM4 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | ACSM4-277M-B | Recombinant Mouse ACSM4 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | ACSM4-475R | Recombinant Rat ACSM4 Protein | Mammalian Cell | His | ||
Rat | ACSM4-131R | Recombinant Rat ACSM4 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | ACSM4-131R-B | Recombinant Rat ACSM4 Protein Pre-coupled Magnetic Beads | HEK293 |
- Involved Pathway
- Protein Function
- Interacting Protein
ACSM4 involved in several pathways and played different roles in them. We selected most pathways ACSM4 participated on our site, such as Butanoate metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACSM4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Butanoate metabolism | ACSM2;ACAT2;GAD1B;BDH2;HMGCS2;ACADS;OXCT2;OXCT1;ACSM5 |
Metabolic pathways | PIP5K1BB;COX6A1;AKR1A1A;ACSL1;ACAT2;MTR;CYP7A1A;AMT;UGT2A1 |
ACSM4 has several biochemical functions, for example, ATP binding, butyrate-CoA ligase activity, fatty-acyl-CoA synthase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ACSM4 itself. We selected most functions ACSM4 had, and list some proteins which have the same functions with ACSM4. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | TSSK3;DDX50;RRM1;ACSM5;CAMK2B1;PKLR;ZAK;NUAK1;NLRP1 |
butyrate-CoA ligase activity | AACS;ACSM3;Acsm2a;ACSM2;ACSM5;ACSM1;ACSM4;PPP1CA;ACSM2B |
fatty-acyl-CoA synthase activity | ACSM4;SLC27A3 |
metal ion binding | PVALB9;FEZF2;ZNHIT1;VPS18;MGAT4B;FAHD1;ESRRGB;MBLAC1;ERI1 |
ACSM4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACSM4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACSM4.
- Q&As
- Reviews
Q&As (10)
Ask a questionACSM4 has been shown to interact with FABP and ABCA1, among other lipid metabolism-related proteins, and may play a role in regulating the transport and metabolism of fatty acids in cells.
ACSM4 has a unique substrate specificity compared to other members of the acyl-CoA synthetase family, preferring long-chain fatty acids with unsaturated bonds.
ACSM4 has been shown to interact with other proteins involved in lipid droplet formation and turnover, such as perilipin and adipose triglyceride lipase (ATGL), and may play a role in promoting the breakdown and utilization of stored lipids.
The regulation of ACSM4 expression is not well understood, but it may be influenced by dietary factors and metabolic status.
ACSM4 has been shown to regulate autophagy, a process by which cells break down and recycle damaged or unnecessary cellular components. Specifically, ACSM4 has been shown to promote the clearance of damaged mitochondria via autophagy in some cell types.
ACSM4 is expressed in a variety of tissues, including the liver, kidney, heart, and skeletal muscle.
ACSM4 has been shown to be a downstream target of AMPK, a key regulator of cellular energy metabolism. AMPK activation can lead to increased ACSM4 expression and activity, which may help cells better respond to metabolic stress.
ACSM4 is thought to play a role in promoting lipid uptake and oxidation in skeletal muscle cells, which can help improve insulin sensitivity and glucose metabolism.
ACSM4 has been implicated in the regulation of inflammation in various tissues. It may play a role in modulating the production of inflammatory cytokines and other mediators.
Studies have suggested that ACSM4 expression may be upregulated in insulin-resistant states, such as obesity and type 2 diabetes. The exact mechanism by which ACSM4 contributes to insulin resistance is not well understood.
Customer Reviews (5)
Write a reviewIts exceptional characteristics and superior performance have greatly enhanced the accuracy and validity of our findings.
Using this protein is like having a cup of coffee with your favorite lab mate. It's comforting, reliable, and gives you that extra boost in your research!
Simplified workflows, increased experimental efficiency.
Quality product, reasonable pricing, and exceptional service. A winning combination.
This protein has proven to be an invaluable asset in our laboratory.
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