Recombinant Human ACTG2 protein, His & T7-tagged
Cat.No. : | ACTG2-6836H |
Product Overview : | Recombinant Human ACTG2 aa. (Glu3~Phe376 (Accession # P63267)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
- Download
Description : | Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides. |
Source : | E. coli |
Species : | Human |
Tag : | His & T7 |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 45.3kDa. |
Protein length : | Glu3~Phe376 (Accession # P63267) |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 5.3. |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | ACTG2 actin, gamma 2, smooth muscle, enteric [ Homo sapiens (human) ] |
Official Symbol : | ACTG2 |
Synonyms : | ACT; ACTE; VSCM; ACTA3; ACTL3; ACTSG; actin-like protein; alpha-actin-3; actin, gamma-enteric smooth muscle |
Gene ID : | 72 |
mRNA Refseq : | NM_001199893.1 |
Protein Refseq : | NP_001186822.1 |
UniProt ID : | P63267 |
Products Types
◆ Recombinant Protein | ||
ACTG2-285M | Recombinant Mouse ACTG2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACTG2-137R | Recombinant Rat ACTG2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACTG2-1243M | Recombinant Mouse ACTG2 Protein | +Inquiry |
ACTG2-6727C | Recombinant Chicken ACTG2 | +Inquiry |
Actg2-3095M | Recombinant Mouse Actg2, His-tagged | +Inquiry |
◆ Lysates | ||
ACTG2-9063HCL | Recombinant Human ACTG2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (18)
Ask a questionACTG2 has been found to have a critical role in HCC tumor metastasis.
Yes, ACTG2 expression can be regulated by various signaling pathways and transcription factors specific to smooth muscle cells.
ACTG2 inhibits cell growth in vitro.
While ACTG2 is primarily expressed in smooth muscle tissues, low levels of expression have also been detected in other tissues, suggesting potential additional functions.
The ACTG2 gene encodes the protein actin gamma-2, which is involved in muscle contraction and smooth muscle function.
Yes, mutations in the ACTG2 gene have been linked to a group of rare disorders called visceral myopathy, which affect the function of smooth muscles in the gastrointestinal tract.
ACTG2 can interact with various proteins involved in cytoskeletal organization and muscle contraction, such as myosin and other actin-binding proteins
ACTG2 is an essential component of the actin cytoskeleton in smooth muscle cells, providing structural support and facilitating the contraction of these muscles.
Yes, ACTG2 is regarded as a novel target for the treatment of HCC.
The discovery of ACTG2's role provides valuable insights for further understanding and potentially treating HCC.
ACTG2 is expressed in a fraction of small intestine neuroendocrine tumors (SI-NETs).
miR-145 positively regulates the expression of ACTG2.
Given its role in smooth muscle function, ACTG2 may hold therapeutic potential for conditions involving smooth muscle dysfunction, such as gastrointestinal motility disorders.
ACTG2 is primarily expressed in smooth muscle tissues, including the smooth muscle cells of the gastrointestinal tract, blood vessels, and uterus.
Symptoms of ACTG2-related visceral myopathy can include gastrointestinal dysmotility, constipation, difficulty swallowing, and other digestive issues.
The ACTG2 protein belongs to the actin family and has a globular structure composed of multiple subunits that form filaments.
Yes, targeting ACTG2 holds promise as a potential therapeutic approach for treating HCC.
The findings suggest potential therapeutic strategies for small intestine neuroendocrine tumors (SI-NETs) based on ACTG2 and its regulation by miR-145.
Customer Reviews (5)
Write a reviewOur experiments consistently demonstrate that the protein product effectively promotes cell proliferation and growth.
The purity of the protein is evident from the absence of any contaminants, ensuring reliable and accurate results.
We have used the protein product across multiple experiments, and its performance has remained consistent throughout.
The shipping process was expedited, ensuring timely delivery of the product to our laboratory.
The company's customer support team has been extremely helpful, promptly addressing any technical or scientific inquiries.
Ask a Question for All ACTG2 Products
Required fields are marked with *
My Review for All ACTG2 Products
Required fields are marked with *
Inquiry Basket