Recombinant Human ACVR2B protein(Met1-Thr134), His-tagged
Cat.No. : | ACVR2B-197H |
Product Overview : | Recombinant Human ACVR2B (NP_001097.2) (Met 1-Thr 134) was expressed in HEK293, fused with a polyhistidine tag at the C-terminus. |
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Source : | HEK293 |
Species : | Human |
Tag : | C-His |
Protein length : | Met1-Thr134 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | 1. Measured by its ability to bind biotinylated Human INHBA-his in functional ELISA. 2. Measured by its ability to bind biotinylated Mouse INHBA-his in functional ELISA. 3. Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.3-2 μg/mL in the presence of 10 ng/mL recombinant Activin A. |
Molecular Mass : | The recombinant human ACVR2B comprises 127 amino acids and predicts a molecular mass of 15 kDa. As a result of glycosylation, rh ACVR2B migrates as an approximately 33-38 kDa protein in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 97 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | ACVR2B activin A receptor, type IIB [ Homo sapiens ] |
Official Symbol : | ACVR2B |
Synonyms : | ACVR2B; activin A receptor, type IIB; activin receptor type-2B; ActR IIB; HTX4; ACTRIIB; ActR-IIB; |
Gene ID : | 93 |
mRNA Refseq : | NM_001106 |
Protein Refseq : | NP_001097 |
MIM : | 602730 |
UniProt ID : | Q13705 |
Products Types
◆ Recombinant Protein | ||
ACVR2B-3386C | Active Recombinant Cynomolgus ACVR2B protein(Ser28-Thr143), His-tagged | +Inquiry |
ACVR2B-011M | Active Recombinant Mouse ACVR2B Protein, Fc-tagged | +Inquiry |
ACVR2B-1155H | Recombinant Human ACVR2B Protein, MYC/DDK-tagged | +Inquiry |
ACVR2B-02H | Recombinant Active Human ACVR2B Protein, GST-tagged | +Inquiry |
ACVR2B-275H | Recombinant Human ACVR2B Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ACVR2B-2540MCL | Recombinant Mouse ACVR2B cell lysate | +Inquiry |
ACVR2B-2724HCL | Recombinant Human ACVR2B cell lysate | +Inquiry |
ACVR2B-734CCL | Recombinant Cynomolgus ACVR2B cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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