Recombinant Human ACVRL1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | ACVRL1-1117H |
Product Overview : | ACVRL1 MS Standard C13 and N15-labeled recombinant protein (NP_001070869) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 56.1 kDa |
AA Sequence : | MTLGSPRKGLLMLLMALVTQGDPVK PSRGPLVTCTCESPHCKGPTCRGAW CTVVLVREEGRHPQEHRGCGNLHRE LCRGRPTEFVNHYCCDSHLCNHNVS LVLEATQPPSEQPGTDGQLALILGP VLALLALVALGVLGLWHVRRRQEKQ RGLHSELGESSLILKASEQGDSMLG DLLDSDCTTGSGSGLPFLVQRTVAR QVALVECVGKGRYGEVWRGLWHGES VAVKIFSSRDEQSWFRETEIYNTVL LRHDNILGFIASDMTSRNSSTQLWL ITHYHEHGSLYDFLQRQTLEPHLAL RLAVSAACGLAHLHVEIFGTQGKPA IAHRDFKSRNVLVKSNLQCCIADLG LAVMHSQGSDYLDIGNNPRVGTKRY MAPEVLDEQIRTDCFESYKWTDIWA FGLVLWEIARRTIVNGIVEDYRPPF YDVVPNDPSFEDMKKVVCVDQQTPT IPNRLAADPVLSGLAQMMRECWYPN PSARLTALRIKKTLQKISNSPEKPK VIQTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | ACVRL1 activin A receptor type II-like 1 [ Homo sapiens (human) ] |
Official Symbol : | ACVRL1 |
Synonyms : | ACVRL1; activin A receptor type II-like 1; ACVRLK1, ORW2; serine/threonine-protein kinase receptor R3; ALK1; HHT; HHT2; activin receptor-like kinase 1; TGF-B superfamily receptor type I; activin A receptor, type II-like kinase 1; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1; |
Gene ID : | 94 |
mRNA Refseq : | NM_001077401 |
Protein Refseq : | NP_001070869 |
MIM : | 601284 |
UniProt ID : | P37023 |
Products Types
◆ Recombinant Protein | ||
ACVRL1-090H | Recombinant Human ACVRL1 Protein, His-tagged | +Inquiry |
Acvrl1-530M | Recombinant Mouse Acvrl1 Protein, MYC/DDK-tagged | +Inquiry |
Acvrl1-2M | Recombinant Mouse Acvrl1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACVRL1-1186C | Active Recombinant Cynomolgus ACVRL1 protein(Met1-Gln118), His-tagged | +Inquiry |
ACVRL1-152R | Recombinant Rat ACVRL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ACVRL1-3001RCL | Recombinant Rat ACVRL1 cell lysate | +Inquiry |
ACVRL1-3093MCL | Recombinant Mouse ACVRL1 cell lysate | +Inquiry |
ACVRL1-1191CCL | Recombinant Cynomolgus ACVRL1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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