Recombinant Human ADAM11 Protein, GST-tagged

• Cat.No.: ADAM11-273H
• Product Overview: Human ADAM11 partial ORF ( NP_002381, 230 a.a. - 333 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 37.18 kDa
• AA Sequence: GHPTVHSETKYVELIVINDHQLFEQ MRQSVVLTSNFAKSVVNLADVIYKE QLNTRIVLVAMETWADGDKIQVQDD LLETLARLMVYRREGLPEPSDATHL FSGR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ADAM11 ADAM metallopeptidase domain 11 [ Homo sapiens ]
• Official Symbol: ADAM11
• Synonyms: ADAM11; ADAM metallopeptidase domain 11; a disintegrin and metalloproteinase domain 11 , MDC; disintegrin and metalloproteinase domain-containing protein 11; metalloproteinase like; disintegrin like; cysteine rich protein; ADAM 11; MDC
• Gene ID: 4185
• mRNA Refseq: NM_002390
• Protein Refseq: NP_002381
• MIM: 155120
• UniProt ID: O75078

Reviews

04/10/2022

The ADAM11 proteins purchased from your company is suitable for ELISA.

02/25/2021

The staff had a good attitude, actively communicated with me and solved many technical problems.

Q&As

Where ADAM11 is highly expressed?

ADAM11 is widely expressed in hippocampus and cerebellum。

Where ADAM11 protein is abundantly expressed in humans?

ADAM11 is abundantly expressed in the cerebellar cortex and spinal cord, and is also expressed in small amounts in the retina and liver.

Which membrane is recommended for WB of ADAM11 protein?

You can choose PVDF membranes for western blotting.