Recombinant Human ADAM18, His-tagged

• Cat.No.: ADAM18-9371H
• Product Overview: Recombinant Human ADAM18 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a sperm surface protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 338-687a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ADAM18 ADAM metallopeptidase domain 18 [ Homo sapiens ]
• Official Symbol: ADAM18
• Synonyms: ADAM18; ADAM metallopeptidase domain 18; a disintegrin and metalloproteinase domain 18; disintegrin and metalloproteinase domain-containing protein 18; putative ADAM18 gene product; ADAM27; tMDCIII; disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; tMDC III; transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; MGC41836; MGC88272
• Gene ID: 8749
• mRNA Refseq: NM_001190956
• Protein Refseq: NP_001177885
• UniProt ID: Q9Y3Q7
• Chromosome Location: 8p11.22
• Function: metalloendopeptidase activity; metallopeptidase activity; zinc ion binding

Reviews

06/11/2022

A protein product that meets my needs, and also has a very good after-sales service.

07/05/2021

The protein products arrived quickly and the experiment worked well.

04/22/2021

I am very grateful to the technical staff for their help in my experiments, and of course the quality of the protein products is also very good.

08/04/2020

The high purity of the product meets my requirements.

Q&As

Do you offer other protein products from ADAM subfamily B?

We provide ADAM2, ADAM9, ADAM32 which belong to ADAM subfamily B.

Can the tag be replaced with another one?

Yes, we can customize the tag according to your needs.

Which disease-related researches is ADAM18 currently used in?

ADAM18 is currently used in multiple myeloma, leukemia, uterine leiomyomas, diabetic retinopathy and other related research.

How long does it usually take to arrive after purchase?

We will ship the products in stock as soon as possible after purchase, but the specific arrival time is related to your address.

Is this product a lyophilized powder or a liquid?

We will ship according to the inventory, if you have a request for this, you can also explain to us in advance.

Can the tag be removed?

Yes, we can remove tags according to your needs.

Can the Tag type and tag location be customized according to my requirements?

Yes, you can communicate your specific customization requirements directly with our experts.

Will there be detailed information on protein storage and post-receipt handling in the product insert?

It provides relevant information, and you can also consult relevant questions to our experts.

Do you offer ADAM18 fused with other tags?

We can customize ADAM18 with other tags according to your requirements.

Do you provide reagents related to protein preservation?

We currently do not provide such reagent products.