Description : |
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
His |
Form : |
Lyophilized |
Molecular Mass : |
71.6 kDa |
Protein Length : |
824 |
AA Sequence : |
MRGLGLWLLGAMMLPAIAPSRPWAL MEQYEVVLPRRLPGPRVRRALPSHL GLHPERVSYVLGATGHNFTLHLRKN RDLLGSGYTETYTAANGSEVTEQPR GQDHCFYQGHVEGYPDSAASLSTCA GLRGFFQVGSDLHLIEPLDEGGEGG RHAVYQAEHLLQTAGTCGVSDDSLG SLLGPRTAAVFRPRPGDSLPSRETR YVELYVVVDNAEFQMLGSEAAVRHR VLEVVNHVDKLYQKLNFRVVLVGLE IWNSQDRFHVSPDPSVTLENLLTWQ ARQRTRRHLHDNVQLITGVDFTGTT VGFARVSAMCSHSSGAVNQDHSKNP VGVACTMAHEMGHNLGMDHDENVQG CRCQERFEAGRCIMAGSIGSSFPRM FSDCSQAYLESFLERPQSVCLANAP DLSHLVGGPVCGNLFVERGEQCDCG PPEDCRNRCCNSTTCQLAEGAQCAH GTCCQECKVKPAGELCRPKKDMCDL EEFCDGRHPECPEDAFQENGTPCSG GYCYNGACPTLAQQCQAFWGPGGQA AEESCFSYDILPGCKASRYRADMCG VLQCKGGQQPLGRAICIVDVCHALT TEDGTAYEPVPEGTRCGPEKVCWKG RCQDLHVYRSSNCSAQCHNHGVCNH KQECHCHAGWAPPHCAKLLTEVHAA SGSLPVLVVVVLVLLAVVLVTLAGI IVYRKARSRILSRNVAPKTTMGRSN PLFHQAASRVPAKGGAPAPSRGPQE LVPTTHPGQPARHPASSVALKRPPP APPVTVSSPPFPVPVYTRQAPKQVI KPTFAPPVPPVKPGAGAANPGPAEG AVGPKVALKPPIQRKQGAGAPTAP |
Purity : |
> 98% |
Applications : |
WB; ELISA; FACS; FC |
Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
Storage : |
At -20 centigrade. |
Concentration : |
1 mg/mL |
Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |