Recombinant Human ADAMTS1, GST-tagged
Cat.No. : | ADAMTS1-105H |
Product Overview : | Recombinant Human ADAMTS1 was expressed as gst-tagged fusion protein by E.Coli and puri?ed by GSH-sepharose. |
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Description : | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 253-546aa |
Storage : | The protein is stored in PBS buffer at -20oC. Repeated freezethaw cycles should be avoided. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 [ Homo sapiens (human) ] |
Official Symbol : | ADAMTS1 |
Synonyms : | ADAMTS1; C3-C5; METH1; ADAM metallopeptidase with thrombospondin type 1 motif, 1; A disintegrin and metalloproteinase with thrombospondin motifs 1; METH-1; ADAM-TS1; ADAMTS-1; ADAM-TS 1; human metalloproteinase with thrombospondin type 1 motifs; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1 |
Gene ID : | 9510 |
mRNA Refseq : | NM_006988 |
Protein Refseq : | NP_008919 |
MIM : | 605174 |
UniProt ID : | Q9UHI8 |
Chromosome Location : | 21q21.2 |
Pathway : | Endochondral Ossification |
Function : | heparin binding; metalloendopeptidase activity; metallopeptidase activity |
Products Types
◆ Recombinant Protein | ||
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ADAMTS1-531H | Recombinant Human ADAMTS1, His-tagged | +Inquiry |
ADAMTS1-62R | Recombinant Rhesus Macaque ADAMTS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADAMTS1-295H | Active Recombinant Human ADAMTS1 Protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (11)
Ask a questionPro-peptide, metallo proteinase, depolymerase/cysteine enriched region, spacer region and thrombospondin type I repeat.
Yes, you can first communicate with our experts for customized requirements.
The delivery cycle of this kind of protein is related to your specific customization requirements, you can communicate with our experts first.
We can provide ADAMTS1 protein fused with other tags.
ADAMTS1 applied to a variety of diseases including colon, oesophageal and lung cancers.
ADAMTS1 is involved in the physiological and pathological processes of human growth and development, the formation of the urinary and reproductive systems, and the development of tumours in tissues and organs.
Inactivation of ADAMTS1 causes infertility and developmental delay in females.
Yes, all ADAMTS1 proteins are currently discounted.
ADAMTS1 degrades extracellular matrix proteins such as versican , aggrecan , syndecan and nidogen.
Yes, our team can customize the protein according to your requirements.
Trehalose can prevent protein secondary structure changes, elongation and aggregation during freeze-drying.
Customer Reviews (3)
Write a reviewExcellent after-sales service, solving many experimental problems.
The products provided by your company are inexpensive and of high quality, and because of this, my experiments could be completed successfully.
The price of the product is right and the quality meets my research needs.
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