Recombinant Human ADAMTS16 protein, His & T7-tagged

• Cat.No.: ADAMTS16-1471H
• Product Overview: Recombinant Human ADAMTS16 aa. (Leu290~Pro641 (Accession # Q8TE57)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may inhibit chondrosarcoma cell proliferation and migration. This gene may regulate blood pressure.
• Source: E. coli
• Species: Human
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 42.6kDa
• Protein length: Leu290~Pro641 (Accession # Q8TE57)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 8.2

Gene Information

• Gene Name: ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif 16 [ Homo sapiens (human) ]
• Official Symbol: ADAMTS16
• Synonyms: ADAMTS16; ADAM metallopeptidase with thrombospondin type 1 motif 16; ADAMTS16s; A disintegrin and metalloproteinase with thrombospondin motifs 16; ADAM-TS 16; ADAM-TS16; ADAMTS-16; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 16
• Gene ID: 170690
• mRNA Refseq: NM_139056.3
• Protein Refseq: NP_620687.2
• UniProt ID: Q8TE57

Reviews

04/17/2022

The price is affordable, and the protein purity also meets the product information.

02/08/2022

Skilled customer service business skills, smooth communication, fully understand the purchase needs of customer service.

06/09/2021

The purchased ADAMTS16 protein is suitable for WB experiments and I am satisfied with the results.

07/03/2020

Customer service followed up on the progress of my experiment in real time and ensured that my experiment went smoothly.

Q&As

Do you offer ADAMTS16 with other tags?

We can customize the production of ADAMTS16 according to your needs.

When will it be shipped?

We will ship as soon as possible after your purchase.

Does ADAMTS16 protein have protease activity?

Yes, ADAMTS16 has protease activity, and he can cleave α2- macroglobulin.

I want to buy ADAMTS16 for WB, do you offer it?

We offer ADAMTS16 for Western blotting.

Does ADAMTS16 interact with LAP-TGF-β1?

Yes, overexpression of ADAMTS16 promotes activation of LAP-TGF-β1.

What are the main applications of ADAMTS16 in the study of diseases?

ADAMTS16 is currently used mainly in cardiovascular disease research.

Where is ADAMTS16 primarily expressed?

ADAMTS16 is expressed at high levels in fetal lung and kidney and in adult brain and ovary.

What protein does ADAMTS16 have the highest homology with?

ADAMTS16 has the highest homology with ADAMTS18.