Recombinant Human ADAMTS18 protein(913-1040aa), His-GST&Myc-tagged

• Cat.No.: ADAMTS18-4326H
• Product Overview: Recombinant Human ADAMTS18 protein(Q8TE60)(913-1040aa), fused with N-terminal His and GST tag and C-terminal Myc tag, was expressed in E.coli.

Specification

• Source: E.coli
• Species: Human
• Tag: N-His-GST&C-Myc
• Protein length: 913-1040aa
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 49.1 kDa
• AASequence: CSAKTKPVTEPKICNAFSCPAYWMP GEWSTCSKACAGGQQSRKIQCVQKK PFQKEEAVLHSLCPVSTPTQVQACN SHACPPQWSLGPWSQCSKTCGRGVR KRELLCKGSAAETLPESQCTSLPRP ELQ
• Purity: Greater than 85% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.

Gene Information

• Gene Name: ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 [ Homo sapiens ]
• Official Symbol: ADAMTS18
• Synonyms: ADAMTS18; ADAM metallopeptidase with thrombospondin type 1 motif, 18; a disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 18 , ADAMTS21; A disintegrin and metalloproteinase with thrombospondin motifs 18; disintegrin and metalloprotease-like protein; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 18; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 21; KNO2; ADAMTS21
• Gene ID: 170692
• mRNA Refseq: NM_199355
• Protein Refseq: NP_955387
• MIM: 607512
• UniProt ID: Q8TE60

Reviews

11/19/2022

The delivery was fast, which solved my urgent needs.

05/09/2021

The ADAMTS18 proteins purchased from your company is suitable for ELISA.

05/05/2021

Purchased the right product at the right price and with the best quality.

08/13/2020

The technicians understand the customer's experimental needs and have helped me to solve many of the problems that have arisen during the experiments.

Q&As

Do you provide technical guidance on the use of recombinant proteins?

We will provide customers with relevant technical support.

Can the Tag and tag location of human ADAMTS18 be customized according to my requirements?

Yes, we will provide custom-manufactured recombinant proteins according to your requirements.

What is the structure domain of ADAMTS18?

The structure of ADAMTS18 includes a signal peptide, a prodomain, a metalloproteinase domain, a disintegrin-like domain, a TSP1, a cysrich domain, a spacer and a TSP1-like repeat.

Is ADAMTS18 widely used in disease research?

ADAMTS18 has been more frequently studied in esophageal cancer, osteosarcoma and endometrial cancer.

In which tissues is ADAMTS18 abundantly expressed?

ADAMTS18 is mainly expressed in adult brain, prostate and retina tissues.

How do you purify the protein?

We have adopted multiple purification methods, including hydrophobic chromatography, affinity chromatography, ion exchange chromatography, salting out, molecular sieve, etc.

What is the biological function of ADAMTS18?

Expression of ADAMTS18 reduced cancer cell replication and growth, suggesting that it has a tumor-suppressive effect.

Where is the cellular localization of ADAMTS18?

ADAMTS18 is mainly localized in the cytoplasm.