Recombinant Human ADAMTS19 protein, His-tagged

• Cat.No.: ADAMTS19-1468H
• Product Overview: Recombinant Human ADAMTS19 aa. (Tyr325~Pro686) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Description: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS16, another family member.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: 44kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Tyr325~Pro686
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP; CoIP; Purification; Amine Reactive Labeling.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Concentration: 200μg/mL
• Storage buffer: 100mM NaHCO3, 500mM NaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.
• Reconstitution: Reconstitute in 100mM NaHCO3, 500mM NaCl (pH8.3) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
• Isoelectric Point: 5.8

Gene Information

• Gene Name: ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif 19 [ Homo sapiens (human) ]
• Official Symbol: ADAMTS19
• Synonyms: ADAMTS19; ADAM metallopeptidase with thrombospondin type 1 motif 19; A disintegrin and metalloproteinase with thrombospondin motifs 19; ADAM-TS 19; ADAM-TS19; ADAMTS-19; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 19
• Gene ID: 171019
• mRNA Refseq: NM_133638.4
• Protein Refseq: NP_598377.4
• UniProt ID: Q8TE59

Reviews

03/24/2022

Good product and affordable price.

09/11/2021

In response to the problems in the experiment, the technician gave a satisfactory solution.

04/10/2021

Big company with guaranteed after-sales service., customers buy with confidence.

05/14/2020

ADAMTS19 proteins purchased are as advertised and the quality of the product is guaranteed.

Q&As

Do you provide ADAMTS19 with tags other than his?

We can provide ADAMTS19 fused with other tags.

How is ADAMTS19 expressed in gastric cancer?

ADAMTS19 is downregulated in human gastric cancer.

Where is the cellular localization of ADAMTS19?

ADAMTS19 is mainly localized in the cytoplasm.

Is ADAMTS19 in stock? When can it be shipped?

ADAMTS19 is in stock. We will arrange delivery after you purchase.

What is the biological function of ADAMTS19?

ADAMTS19 suppressed cell migration and invasion in vitro.

What are the effects of silencing ADAMTS19?

Silencing of ADAMTS19 promotes proliferation, invasion and migration of Ishikawa cells in vitro.

Does ADAMTS19 interact with P65?

ADAMTS19 binds with cytoplasm P65, decreasing the nucleus phosphorylation of P65.

In which diseases is ADAMTS19 currently used in research?

ADAMTS19 applied to endometrial cancer and colorectal cancer is more researched.

I need to buy ADAMTS19 for WB, do you also provide corresponding antibodies and reagents?

We mainly provide recombinant protein products, but we can give you relevant advice.