Recombinant Human ADH5 Protein (2-374 aa), His-tagged
Cat.No. : | ADH5-1317H |
Product Overview : | Recombinant Human ADH5 Protein (2-374 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Metabolism. Protein Description: Full Length of Mature Protein. |
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Description : | Class-III ADH is rarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. |
Source : | Yeast |
Species : | Human |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 41.6 kDa |
Protein length : | 2-374 aa |
AA Sequence : | ANEVIKCKAAVAWEAGKPLSIEEIE VAPPKAHEVRIKIIATAVCHTDAYT LSGADPEGCFPVILGHEGAGIVESV GEGVTKLKAGDTVIPLYIPQCGECK FCLNPKTNLCQKIRVTQGKGLMPDG TSRFTCKGKTILHYMGTSTFSEYTV VADISVAKIDPLAPLDKVCLLGCGI STGYGAAVNTAKLEPGSVCAVFGLG GVGLAVIMGCKVAGASRIIGVDINK DKFARAKEFGATECINPQDFSKPIQ EVLIEMTDGGVDYSFECIGNVKVMR AALEACHKGWGVSVVVGVAASGEEI ATRPFQLVTGRTWKGTAFGGWKSVE SVPKLVSEYMSKKIKVDEFVTHNLS FDEINKAFELMHSGKSIRTVVKI |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. |
Gene Name : | ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide [ Homo sapiens ] |
Official Symbol : | ADH5 |
Synonyms : | ADH5; ADH 3; ADHX; FDH; ADH-3; FALDH; GSNOR; GSH-FDH; |
Gene ID : | 128 |
mRNA Refseq : | NM_000671 |
Protein Refseq : | NP_000662 |
MIM : | 103710 |
UniProt ID : | P11766 |
Products Types
◆ Recombinant Protein | ||
ADH5-26H | Recombinant Human ADH5 Protein, His-tagged | +Inquiry |
ADH5-284H | Recombinant Human ADH5 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADH5-0257H | Recombinant Human ADH5 Protein (M1-I374), GST tagged | +Inquiry |
Adh5-543M | Recombinant Mouse Adh5 Protein, MYC/DDK-tagged | +Inquiry |
ADH5-0256H | Recombinant Human ADH5 Protein (M1-I374), Tag Free | +Inquiry |
◆ Lysates | ||
ADH5-30HCL | Recombinant Human ADH5 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionADH5 exhibits a tissue-specific expression pattern, and its expression is regulated by various factors such as transcriptional control and signaling pathways.
ADH5 can efficiently metabolize different alcohol substrates, and its substrate specificity may differ from other ADH enzymes.
ADH5 expression and activity can be influenced by chronic alcohol exposure or withdrawal, and studying the underlying molecular mechanisms can shed light on alcohol-related effects.
The activity or function of ADH5 can potentially be modulated by pharmacological agents or environmental factors, presenting potential therapeutic implications.
Interacting proteins or cofactors can modulate the activity or function of ADH5, and investigating the molecular mechanisms involved can enhance our understanding of its regulation.
The enzymatic kinetics and catalytic properties of ADH5 contribute to its overall activity and efficiency in alcohol metabolism.
ADH5 may have implications in the metabolism of other endogenous compounds or xenobiotics, suggesting its involvement in broader physiological functions.
Genetic variations or polymorphisms in the ADH5 gene may impact alcohol metabolism and susceptibility to alcohol-related disorders, emphasizing the role of genetic factors in its function.
The structural features of ADH5 play a crucial role in its catalytic activity and binding affinity for alcohol, and understanding these features provides insights into its function.
Exploring the consequences of ADH5 deficiency or overexpression provides insights into its role in alcohol metabolism and its impact on physiological processes.
Customer Reviews (2)
Write a reviewHighly effective in stabilizing and enhancing the activity of enzymes in enzyme engineering.
Demonstrates excellent resistance to aggregation and aggregation-prone conditions.
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