Recombinant Human AEBP2, His-tagged
Cat.No. : | AEBP2-9452H |
Product Overview : | Recombinant Human AEBP2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 1-295a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | AEBP2 AE binding protein 2 [ Homo sapiens ] |
Official Symbol : | AEBP2 |
Synonyms : | AEBP2; AE binding protein 2; zinc finger protein AEBP2; MGC17922; AE-binding protein 2; adipocyte enhancer-binding protein 2; AE(adipocyte enhancer)-binding protein 2; |
Gene ID : | 121536 |
mRNA Refseq : | NM_001114176 |
Protein Refseq : | NP_001107648 |
UniProt ID : | Q6ZN18 |
Chromosome Location : | 12p12.3 |
Function : | DNA binding; metal ion binding; transcription corepressor activity; zinc ion binding; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionDysregulation or dysfunction of AEBP2 protein can disrupt cellular processes, including embryonic development or stem cell differentiation, and contribute to the development of developmental disorders or cancer.
The tissue-specific expression patterns of AEBP2 protein vary across different organs and cell types. Factors regulating its expression levels include transcriptional control and signaling pathways.
Experimental techniques such as gene expression analysis, chromatin immunoprecipitation, knockout or overexpression studies, and functional assays have been employed to investigate the functional significance of AEBP2 protein.
AEBP2 protein plays a role in various cellular processes, including embryonic development, stem cell regulation, and epigenetic control of gene expression, by modulating chromatin structure and transcriptional activity.
The subcellular localization of AEBP2 protein is determined by specific mechanisms and targeting sequences, which facilitate its transport and localization to specific cellular compartments.
Genetic variations or mutations in the AEBP2 gene may impact the expression or function of AEBP2 protein, potentially contributing to altered cellular processes and disease susceptibility.
AEBP2 protein exhibits DNA-binding activity, recognizing specific DNA sequences or binding motifs, such as AT-rich elements, that regulate gene expression and chromatin organization.
Post-translational modifications, such as phosphorylation or methylation, and regulatory factors modulate the activity or stability of AEBP2 protein, impacting its function and cellular responses.
AEBP2 protein interacts with other proteins, such as transcription factors or chromatin modifiers, forming protein complexes that influence gene expression and cellular processes.
The structural features or domains of AEBP2 protein, including the DNA-binding domain, transcriptional repression domains, and interaction regions, are critical for its function and interaction with other molecules in cellular processes.
Customer Reviews (3)
Write a reviewDetecting protein-protein interactions in DNA binding and transcriptional regulation.
Understanding protein-protein interaction networks in cell death signaling.
Exploring protein-protein interactions involved in mitochondrial dysfunction.
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