Recombinant Human AFAP1, His-tagged
Cat.No. : | AFAP1-200H |
Product Overview : | AFAP1, 250-588aa, Human, His tag, E.coli |
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Description : | AFAP1 is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human AFAP1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.4M Urea |
Molecular Mass : | 39.2 kDa(360aa) |
Protein length : | 250-588aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGCSGPVDSE CPPPPSSPVH KAELEKKLSS ERPSSDGEGV VENGITTCNG KEQVKRKKSS KSEAKGTVSK VTGKKITKII SLGKKKPSTD EQTSSAEEDV PTCGYLNVLS NSRWRERWCR VKDNKLIFHK DRTDLKTHIV SIPLRGCEVI PGLDCKHPLT FRLLRNGQEV AVLEASSSED MGRWIGILLA ETGSSTDPEA LHYDYIDVEM SASVIQTAKQ TFCFMNRRVI SANPYLGGTS NGYAHPSGTA LHYDDVPCIN GSLRGKKPPV ASNGVTGKGK TLSSQPKKAD PAAVVKRTGS NAAQYKYGKN RVEADAKRLQ TKEEELLKRK EALRNRLAQL |
Purity : | >80% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5mg/ml (determined by Bradford assay) |
Gene Name : | AFAP1 actin filament associated protein 1 [ Homo sapiens ] |
Official Symbol : | AFAP1 |
Synonyms : | AFAP1; actin filament associated protein 1; actin filament-associated protein 1; AFAP; AFAP 110; 110 kDa actin filament-associated protein; actin filament-associated protein, 110 kDa; AFAP110; AFAP-110; FLJ56849; |
Gene ID : | 60312 |
mRNA Refseq : | NM_001134647 |
Protein Refseq : | NP_001128119 |
MIM : | 608252 |
UniProt ID : | Q8N556 |
Chromosome Location : | 4p16 |
Function : | actin binding; |
Products Types
◆ Recombinant Protein | ||
Afap1-496M | Recombinant Mouse Afap1 Protein, His-tagged | +Inquiry |
AFAP1-209R | Recombinant Rat AFAP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
AFAP1-543H | Recombinant Human AFAP1 Protein, His-tagged | +Inquiry |
AFAP1-374M | Recombinant Mouse AFAP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
AFAP1-553R | Recombinant Rat AFAP1 Protein | +Inquiry |
◆ Lysates | ||
AFAP1-8990HCL | Recombinant Human AFAP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionAFAP1 protein contributes to disease development or pathophysiological conditions, and the underlying molecular mechanisms are currently being investigated.
Dysregulation or dysfunction of AFAP1 protein can disrupt cellular homeostasis, perturb molecular signaling networks, and contribute to disease progression.
AFAP1 protein holds potential as a target for modulating cellular processes, and further research is needed to explore its therapeutic implications and potential interventions.
AFAP1 protein interacts with specific molecules or forms protein complexes, which have functional implications in various cellular processes.
AFAP1 protein plays a role in cellular processes such as cytoskeletal dynamics, cell migration, or signal transduction, and its function can be investigated experimentally using techniques like siRNA knockdown or overexpression studies.
The subcellular localization of AFAP1 protein can be experimentally determined using techniques such as immunofluorescence microscopy or subcellular fractionation.
Various experimental techniques or assays, such as co-immunoprecipitation, live-cell imaging, or functional assays, have been used to study the functional significance of AFAP1 protein.
Post-translational modifications and regulatory mechanisms modulate the activity or stability of AFAP1 protein.
Genetic variations or mutations in the gene encoding AFAP1 protein may impact its expression or function, influencing cellular processes or disease susceptibility.
The expression of AFAP1 protein is regulated, and specific factors or signaling pathways are involved in its expression control.
Customer Reviews (3)
Write a reviewUnraveling protein-protein interactions in RNA processing for gene expression control.
Mapping protein-protein interactions in DNA transcription for gene regulation.
Investigating protein-protein interactions in autophagy pathways for cellular homeostasis.
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