AFAP1
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Official Full Name
actin filament associated protein 1
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Overview
The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
AFAP1; actin filament associated protein 1; actin filament-associated protein 1; AFAP; AFAP 110; 110 kDa actin filament associated protein; 110 kDa actin filament-associated protein; Actin filament associated protein 110 kDa; AFAP 1; AFAP-110; AFAP1_HUMAN; FLJ56849; actin filament-associated protein, 110 kDa;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | AFAP1-200H | Recombinant Human AFAP1, His-tagged | E.coli | His | 250-588aa | |
Human | AFAP1-9455H | Recombinant Human AFAP1, His-tagged | E.coli | His | C-term-349a.a. | |
Human | AFAP1-543H | Recombinant Human AFAP1 Protein, His-tagged | E.coli | His | ||
Human | AFAP1-400H | Recombinant Human AFAP1 Protein, GST-tagged | Wheat Germ | GST | ||
Human | AFAP1-8990HCL | Recombinant Human AFAP1 293 Cell Lysate | HEK293 | N/A | ||
Human | AFAP1-987HF | Recombinant Full Length Human AFAP1 Protein, GST-tagged | In Vitro Cell Free System | GST | 730 amino acids | |
Mouse | AFAP1-1397M | Recombinant Mouse AFAP1 Protein | Mammalian Cell | His | ||
Mouse | Afap1-496M | Recombinant Mouse Afap1 Protein, His-tagged | E.coli | His | Cys352~Glu572 | |
Mouse | AFAP1-374M | Recombinant Mouse AFAP1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | AFAP1-374M-B | Recombinant Mouse AFAP1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | AFAP1-553R | Recombinant Rat AFAP1 Protein | Mammalian Cell | His | ||
Rat | AFAP1-209R-B | Recombinant Rat AFAP1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | AFAP1-209R | Recombinant Rat AFAP1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Chicken | AFAP1-5779C | Recombinant Chicken AFAP1 | Mammalian Cell | His | ||
Chicken | AFAP1-3864C | Recombinant Chicken AFAP1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
AFAP1 involved in several pathways and played different roles in them. We selected most pathways AFAP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AFAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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AFAP1 has several biochemical functions, for example, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AFAP1 itself. We selected most functions AFAP1 had, and list some proteins which have the same functions with AFAP1. You can find most of the proteins on our site.
Function | Related Protein |
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actin binding | MYO19;TNS4;CAPZB;VASPA;DIXDC1;DIAP3;EPS8;SHROOM3;NEXN |
AFAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AFAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AFAP1.
Tpx2; MYO1C; Flot1; GAK; MYC; FLNA; CDK2; MYH9; IQGAP1; CAPZA2; Tpm1; Actb; Rab5b; PPP1CB; Ppp1cb; MAPRE1; DBN1; Flot2
- Q&As
- Reviews
Q&As (10)
Ask a questionAFAP1 protein contributes to disease development or pathophysiological conditions, and the underlying molecular mechanisms are currently being investigated.
Dysregulation or dysfunction of AFAP1 protein can disrupt cellular homeostasis, perturb molecular signaling networks, and contribute to disease progression.
AFAP1 protein holds potential as a target for modulating cellular processes, and further research is needed to explore its therapeutic implications and potential interventions.
AFAP1 protein interacts with specific molecules or forms protein complexes, which have functional implications in various cellular processes.
AFAP1 protein plays a role in cellular processes such as cytoskeletal dynamics, cell migration, or signal transduction, and its function can be investigated experimentally using techniques like siRNA knockdown or overexpression studies.
The subcellular localization of AFAP1 protein can be experimentally determined using techniques such as immunofluorescence microscopy or subcellular fractionation.
Various experimental techniques or assays, such as co-immunoprecipitation, live-cell imaging, or functional assays, have been used to study the functional significance of AFAP1 protein.
Post-translational modifications and regulatory mechanisms modulate the activity or stability of AFAP1 protein.
Genetic variations or mutations in the gene encoding AFAP1 protein may impact its expression or function, influencing cellular processes or disease susceptibility.
The expression of AFAP1 protein is regulated, and specific factors or signaling pathways are involved in its expression control.
Customer Reviews (3)
Write a reviewUnraveling protein-protein interactions in RNA processing for gene expression control.
Mapping protein-protein interactions in DNA transcription for gene regulation.
Investigating protein-protein interactions in autophagy pathways for cellular homeostasis.
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