Recombinant Human AGR2 Protein Pre-coupled Magnetic Beads
Cat.No. : | AGR2-292H-B |
Product Overview : | The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations. |
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Source : | HEK293 |
Species : | Human |
Form : | Solution |
Particle size : | ~2 μm |
Beads Surface : | Hydrophilic |
Capacity : | > 200 pmol rabbit IgG/ mg beads |
Applications : | Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification. |
Stability : | Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. |
Storage : | 2-8℃. Do not to freeze thaw the Beads |
Concentration : | 10mg beads/mL |
Storage Buffer : | PBS buffer |
Gene Name : | AGR2 anterior gradient 2, protein disulphide isomerase family member [ Homo sapiens (human) ] |
Official Symbol : | AGR2 |
Synonyms : | AG2; AG-2; HPC8; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-116 |
Gene ID : | 10551 |
mRNA Refseq : | NM_006408.4 |
Protein Refseq : | NP_006399.1 |
MIM : | 606358 |
UniProt ID : | O95994 |
Products Types
◆ Recombinant Protein | ||
AGR2-292H | Recombinant Human AGR2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Agr2-1560M | Recombinant Mouse Agr2 Protein, Myc/DDK-tagged | +Inquiry |
Agr2-502R | Recombinant Rat Agr2 Protein, His-tagged | +Inquiry |
AGR2-101R | Recombinant Rhesus Macaque AGR2 Protein, His (Fc)-Avi-tagged | +Inquiry |
AGR2-520H | Recombinant Human AGR2 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
AGR2-8972HCL | Recombinant Human AGR2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionHigh levels of AGR2 expression have been associated with poorer prognosis in several types of cancer, indicating its potential as a prognostic biomarker.
AGR2 promotes cancer cell migration and invasion by modulating signaling pathways involved in epithelial-to-mesenchymal transition (EMT) and extracellular matrix remodeling.
AGR2 has been implicated in protein folding, quality control, and secretion of other proteins. It is also involved in cancer progression and metastasis.
AGR2 is upregulated in response to ER stress and helps restore ER homeostasis by promoting protein folding and reducing ER stress-induced apoptosis.
AGR2 acts as a chaperone protein, facilitating the correct folding of secretory proteins and assisting in their quality control before secretion.
Several small molecules and antibodies targeting AGR2 have been developed as potential therapeutic agents, but further research is needed to validate their efficacy.
Some genetic variants in the AGR2 gene have been associated with an increased risk of certain cancers, including prostate and breast cancer.
AGR2 is overexpressed in various cancers, including breast, prostate, lung, and ovarian cancers, and has been associated with tumor growth, invasion, and drug resistance.
AGR2 can activate signaling pathways such as the PI3K/AKT pathway, Wnt/β-catenin pathway, and MAPK/ERK pathway, which are involved in cell survival, proliferation, and migration.
Yes, elevated levels of AGR2 have been detected in the blood and tissue samples of cancer patients, making it a potential biomarker for cancer diagnosis.
Customer Reviews (5)
Write a reviewVery impressed.
Excellent value for its price
The customer support was also excellent, providing prompt assistance when needed.
The customer service was responsive and assisted me with technical questions.
The purity and activity of the protein were exceptional, and it worked perfectly in my experiments.
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