Recombinant Human AIMP1 protein, His-tagged
Cat.No. : | AIMP1-345H |
Product Overview : | Recombinant Human AIMP1 protein (Ala2-Lys312), fused to His tag at N-terminus, was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (AIMP1) is also known as multisynthase complex auxiliary component p43 and endothelial monocyte-activating polypeptide II (EMAP-II). AIMP1 is a cytokine that may be induced by apoptosis and is also released from professional antigen-presenting cells such as dendritic cells. The release of AIMP1 renders the tumor-associated vasculature sensitive to tumor necrosis factor. Furthermore, AIMP1 binds tRNA and stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. This protein possesses inflammatory cytokine activity. Also, AIMP1 negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22 um filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 35.2 kDa. The protein migrates as 36 kDa under reducing (R) condition (SDS-PAGE). |
Protein length : | 311 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | AIMP1 |
Official Symbol : | AIMP1 |
Synonyms : | AIMP1; aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; SCYE1, small inducible cytokine subfamily E, member 1 (endothelial monocyte activating); aminoacyl tRNA synthase complex-interacting multifunctional protein 1; ARS interacting multifunctional protein 1; EMAP II; EMAP 2; EMAPII; p43; ARS-interacting multifunctional protein 1; endothelial monocyte-activating polypeptide 2; multisynthase complex auxiliary component p43; endothelial-monocyte activating polypeptide II; multisynthetase complex auxiliary component p43; small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating); HLD3; EMAP2; SCYE1 |
Gene ID : | 9255 |
mRNA Refseq : | NM_001142415 |
Protein Refseq : | NP_001135887 |
MIM : | 603605 |
UniProt ID : | Q12904 |
Products Types
◆ Recombinant Protein | ||
AIMP1-130A | Active Recombinant Human AIMP1 Protein (166 aa) | +Inquiry |
Aimp1-7399M | Recombinant Mouse Aimp1 protein | +Inquiry |
AIMP1-4429Z | Recombinant Zebrafish AIMP1 | +Inquiry |
SCYE1-2547H | Recombinant Human SCYE1, GST-tagged | +Inquiry |
AIMP1-865G | Recombinant Human Aminoacyl tRNA Synthetase Complex-interacting Multifunctional Protein 1, His-tagged | +Inquiry |
◆ Lysates | ||
AIMP1-578HCL | Recombinant Human AIMP1 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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