Recombinant Human AK3 Protein Pre-coupled Magnetic Beads
Cat.No. : | AK3-2450H-B |
Product Overview : | The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations. |
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Source : | HEK293 |
Species : | Human |
Form : | Solution |
Particle size : | ~2 μm |
Beads Surface : | Hydrophilic |
Capacity : | > 200 pmol rabbit IgG/ mg beads |
Applications : | Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification. |
Stability : | Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. |
Storage : | 2-8℃. Do not to freeze thaw the Beads |
Concentration : | 10mg beads/mL |
Storage Buffer : | PBS buffer |
Gene Name : | AK3 adenylate kinase 3 [ Homo sapiens ] |
Official Symbol : | AK3 |
Gene ID : | 50808 |
mRNA Refseq : | NM_001199852.1 |
Protein Refseq : | NP_001186781.1 |
MIM : | 609290 |
UniProt ID : | B4DP58 |
Products Types
◆ Recombinant Protein | ||
Ak3-1576M | Recombinant Mouse Ak3 Protein, Myc/DDK-tagged | +Inquiry |
AK3-2450H | Recombinant Human AK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
AK3-112R | Recombinant Rhesus Macaque AK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
AK3-37C | Recombinant Cynomolgus Monkey AK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
AK3-422M | Recombinant Mouse AK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
AK3-8947HCL | Recombinant Human AK3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionAK3 protein is a homodimer, meaning it is composed of two identical subunits. Each subunit consists of about 200 amino acids and contains a nucleotide binding domain that enables AK3 to bind to ATP, ADP, and AMP. The protein structure also contains a highly conserved sequence motif found in other adenylate kinases.
Dysregulation of AK3 protein has been implicated in various diseases and conditions. Some examples include cancer, where altered AK3 expression has been observed in certain types of tumors, suggesting its involvement in cancer progression.
AK3 protein has been found to interact with other molecules within the cell. For example, it can interact with adenine nucleotides like ATP, ADP, and AMP, as well as other enzymes involved in energy metabolism. Additionally, studies have suggested potential protein-protein interactions between AK3 and other mitochondrial proteins involved in various cellular processes.
AK3 protein is primarily found in the mitochondria, which are the energy-producing organelles within cells. It is more specifically located in the mitochondrial intermembrane space.
One notable feature of AK3 protein is its ability to reversibly form disulfide bonds under oxidative conditions, which may regulate its activity and localization within the mitochondria. AK3 protein has also been implicated in protecting cells against oxidative stress and apoptosis, suggesting additional roles beyond its energy metabolism function.
There is ongoing research investigating the potential use of AK3 protein as a diagnostic or prognostic marker for certain diseases. For instance, altered expression levels of AK3 have been found in various cancers, indicating its potential as a biomarker for tumor detection or progression. However, further studies are needed to validate its clinical utility as a diagnostic or prognostic marker.
Currently, there are no specific drugs or therapeutic strategies targeting AK3 protein directly. However, understanding the role of AK3 in disease processes may help identify potential targets for drug development and therapeutic interventions in the future.
AK3 protein continues to be an active area of research. Future studies may focus on elucidating the precise molecular mechanisms underlying its role in cancer, mitochondrial disorders, and neurodegenerative diseases. Additionally, researchers may investigate potential therapeutic strategies targeting AK3 or its associated pathways as a means to treat related disorders.
Yes, there have been identified genetic variations and mutations in the AK3 gene. Some variations may alter the activity or expression levels of AK3 protein, potentially affecting its function. These genetic variations can have implications for various diseases and conditions.
While AK3 protein primarily functions in cellular energy metabolism, it can also indirectly influence signaling pathways through the regulation of AMP levels. AMP can activate the AMP-activated protein kinase (AMPK) pathway, which plays a crucial role in cellular energy sensing and regulation. Thus, by modulating AMP levels, AK3 protein may indirectly affect signaling pathways involved in metabolism, cell proliferation, and stress response.
Customer Reviews (4)
Write a reviewThe AK3 protein epitomizes unparalleled quality, positioning itself as an impeccable solution that precisely caters to my experimental requisites.
Its exceptional integrity and consistency instill utmost confidence in obtaining precise and reliable outcomes, thereby propelling my research endeavors to uncharted levels of success.
Their exemplary technical support team stands poised to address any concerns or hurdles that may arise along my experimental path.
In addition to its exceptional quality, the manufacturer behind the AK3 protein sets a new standard for excellence with their unwavering dedication to customer satisfaction.
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