Recombinant Human ALPK1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | ALPK1-2177H |
Product Overview : | ALPK1 MS Standard C13 and N15-labeled recombinant protein (NP_079420) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | This gene encodes an alpha kinase. Mice which were homozygous for disrupted copies of this gene exhibited coordination defects (PMID: 21208416). Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 138.9 kDa |
AA Sequence : | Tag(s)MNNQKVVAVLLQECKQVLDQLLLEA PDVSEEDKSEDQRCRALLPSELRTL IQEAKEMKWPFVPEKWQYKQAVGPE DKTNLKDVIGAGLQQLLASLRASIL ARDCAAAAAIVFLVDRFLYGLDVSG KLLQVAKGLHKLQPATPIAPQVVIR QARISVNSGKLLKAEYILSSLISNN GATGTWLYRNESDKVLVQSVCIQIR GQILQKLGMWYEAAELIWASIVGYL ALPQPDKKGLSTSLGILADIFVSMS KNDYEKFKNNPQINLSLLKEFDHHL LSAAEACKLAAAFSAYTPLFVLTAV NIRGTCLLSYSSSNDCPPELKNLHL CEAKEAFEIGLLTKRDDEPVTGKQE LHSFVKAAFGLTTVHRRLHGETGTV HAASQLCKEAMGKLYNFSTSSRSQD REALSQEVMSVIAQVKEHLQVQSFS NVDDRSYVPESFECRLDKLILHGQG DFQKILDTYSQHHTSVCEVFESDCG NNKNEQKDAKTGVCITALKTEIKNI DTVSTTQEKPHCQRDTGISSSLMGK NVQRELRRGGRRNWTHSDAFRVSLD QDVETETEPSDYSNGEGAVFNKSLS GSQTSSAWSNLSGFSSSASWEEVNY HVDDRSARKEPGKEHLVDTQCSTAL SEELENDREGRAMHSLHSQLHDLSL QEPNNDNLEPSQNQPQQQMPLTPFS PHNTPGIFLAPGAGLLEGAPEGIQE VRNMGPRNTSAHSRPSYRSASWSSD SGRPKNMGTHPSVQKEEAFEIIVEF PETNCDVKDRQGKEQGEEISERGAG PTFKASPSWVDPEGETAESTEDAPL DFHRVLHNSLGNISMLPCSSFTPNW PVQNPDSRKSGGPVAEQGIDPDAST VDEEGQLLDSMDVPCTNGHGSHRLC ILRQPPGQRAETPNSSVSGNILFPV LSEDCTTTEEGNQPGNMLNCSQNSS SSSVWWLKSPAFSSGSSEGDSPWSY LNSSGSSWVSLPGKMRKEILEARTL QPDDFEKLLAGVRHDWLFQRLENTG VFKPSQLHRAHSALLLKYSKKSELW TAQETIVYLGDYLTVKKKGRQRNAF WVHHLHQEEILGRYVGKDYKEQKGL WHHFTDVERQMTAQHYVTEFNKRLY EQNIPTQIFYIPSTILLILEDKTIK GCISVEPYILGEFVKLSNNTKVVKT EYKATEYGLAYGHFSYEFSNHRDVV VDLQGWVTGNGKGLIYLTDPQIHSV DQKVFTTNFGKRGIFYFFNNQHVEC NEICHRLSLTRPSMEKPCTTRTRPL EQKLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | ALPK1 alpha-kinase 1 [ Homo sapiens (human) ] |
Official Symbol : | ALPK1 |
Synonyms : | ALPK1; alpha-kinase 1; alpha-protein kinase 1; FLJ22670; KIAA1527; Lak; lymphocyte alpha kinase; chromosome 4 kinase; lymphocyte alpha-kinase; lymphocyte alpha-protein kinase; LAK; 8430410J10Rik; |
Gene ID : | 80216 |
mRNA Refseq : | NM_025144 |
Protein Refseq : | NP_079420 |
MIM : | 607347 |
UniProt ID : | Q96QP1 |
Products Types
◆ Recombinant Protein | ||
ALPK1-327H | Recombinant Human ALPK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALPK1-001H | Recombinant Human ALPK1 Protein, Myc/DDK-tagged | +Inquiry |
Alpk1-1605M | Recombinant Mouse Alpk1 Protein, Myc/DDK-tagged | +Inquiry |
ALPK1-3097H | Recombinant Human ALPK1 protein, His-tagged | +Inquiry |
ALPK1-491H | Recombinant Human ALPK1 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
ALPK1-8894HCL | Recombinant Human ALPK1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionYes, ALPK1 kinase activity can be modulated by specific small molecule inhibitors that target its ATP-binding site.
ALPK1 influences intracellular signaling cascades such as MAPK and AKT pathways and can modulate the expression of specific target genes.
ALPK1 knockout or overexpression can lead to altered cell morphology, proliferation rates, and cell cycle progression.
ALPK1 is primarily localized in the cytoplasm of human cells.
ALPK1 has been associated with both pro-apoptotic and anti-apoptotic signaling pathways, suggesting a complex role in cellular survival.
Yes, the expression of ALPK1 can be upregulated or downregulated in response to various stress stimuli.
ALPK1 is implicated in promoting cellular proliferation and growth.
ALPK1 has been implicated in regulating cellular migration and invasion in certain cell types.
Phosphorylation is a known post-translational modification that can regulate ALPK1 activity.
Several interacting proteins and signaling pathways have been identified, including protein kinases, phosphatases, and cytoskeletal regulators.
Customer Reviews (3)
Write a reviewHighly effective fusion protein detection.
Exceptional protein-protein interaction analysis.
Specific target detection in immunohistochemistry.
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