Recombinant Human ALX4
Cat.No. : | ALX4-754H |
Product Overview : | Recombinant Human ALX4 full length or partial length protein was expressed. |
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Source : | Mammalian Cells |
Species : | Human |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC. |
Storage Buffer : | PBS buffer |
Gene Name : | ALX4 ALX homeobox 4 [ Homo sapiens ] |
Official Symbol : | ALX4 |
Gene ID : | 60529 |
mRNA Refseq : | NM_021926.3 |
Protein Refseq : | NP_068745.2 |
MIM : | 605420 |
UniProt ID : | Q9H161 |
Products Types
◆ Recombinant Protein | ||
ALX4-2459H | Recombinant Human ALX4 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALX4-5737C | Recombinant Chicken ALX4 | +Inquiry |
ALX4-511H | Recombinant Human ALX4 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
ALX4-8889HCL | Recombinant Human ALX4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionALX4 interacts with various co-regulatory proteins and transcription factors, forming complexes that modulate gene expression and cellular processes critical for embryonic development.
ALX4 recognizes specific DNA binding motifs, such as homeobox motifs, and binds to regulatory regions of target genes to regulate their transcriptional activity.
Gain-of-function or loss-of-function mutations in ALX4 can disrupt normal embryonic development, leading to craniofacial abnormalities, limb defects, or skeletal malformations.
ALX4 binding sites are associated with specific epigenetic modifications, such as DNA methylation or histone modifications, which contribute to the regulation of ALX4-mediated transcriptional activity.
ALX4 integrates with signaling pathways, such as BMP, Wnt, or FGF signaling, to modulate gene expression and influence cellular behaviors during embryogenesis.
Pharmacological or genetic modulation of ALX4 activity may have therapeutic implications for craniofacial disorders, skeletal dysplasias, or regenerative medicine, but further studies are needed to explore these possibilities.
ALX4 forms transcriptional complexes with other transcription factors and co-regulators, such as MSX1 or RUNX2, to coordinate gene expression programs essential for craniofacial development, skeletal patterning, and limb morphogenesis.
ALX4 exhibits a dynamic spatiotemporal expression pattern during embryonic development, with prominent expression in craniofacial structures, limb buds, and axial skeleton.
ALX4 regulates cell proliferation, differentiation, and migration during embryogenesis through various molecular mechanisms, including interactions with cell cycle regulators, morphogen gradients, or cytoskeletal components.
ALX4 regulates the expression of genes involved in craniofacial development, skeletal patterning, and limb formation, including those encoding transcription factors, extracellular matrix components, or signaling molecules.
Customer Reviews (3)
Write a reviewCompatibility with small sample volumes for limited samples.
High specificity in protein target identification.
Stable and reliable reagents for reproducible results.
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