Recombinant Human APBB2 293 Cell Lysate

• Cat.No.: APBB2-8802HCL

Specification

• Description: Antigen standard for amyloid beta (A4) precursor protein-binding, family B, member 2 (APBB2), transcript variant 3 is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
• Source: HEK 293 cells
• Species: Human
• Components: This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
• Size: 0.1 mg
• Storage Instruction: Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
• Applications: ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.

Gene Information

• Gene Name: APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 [ Homo sapiens ]
• Official Symbol: APBB2
• Synonyms: APBB2; amyloid beta (A4) precursor protein-binding, family B, member 2; amyloid beta A4 precursor protein-binding family B member 2; Fe65 like; FE65L; FE65L1; MGC35575; Fe65-like 1; protein Fe65-like 1; DKFZp434E033
• Gene ID: 323
• mRNA Refseq: NM_001166050
• Protein Refseq: NP_001159522
• MIM: 602710
• UniProt ID: Q92870
• Chromosome Location: 4p13
• Function: beta-amyloid binding; protein binding; transcription factor binding

Reviews

10/05/2022

Labeling effect of APBB2 showed excellent performance in Western blot, which can be used for fluorescence labeling.

09/14/2022

Reproducibility of this APBB2 is very good, which can reduce unnecessary repeated experiments and improve experimental efficiency.

10/17/2020

APBB2 produced by them is easy to preserve and has no problem in long-term preservation.

Q&As

Is there a link between APBB2 and genetic factors?

It is not known whether there is a direct relationship between APBB2 s and genetic factors, but complex genetic and environmental interactions may be involved.

Is the therapeutic effect of APBB2 dose-dependent?

The therapeutic effect of APBB2 may be dose-dependent, but the specific dose-response relationship needs further study.

Does APBB2 affect patients' daily life?

The effect of APBB2 varies from patient to patient and may have some impact on daily life, but the specific situation needs to be evaluated on an individual basis.

How to evaluate the efficacy of APBB2 ?

Evaluating the efficacy of APBB2 usually requires clinical trials and animal studies to observe its impact on disease models and therapeutic efficacy.

Can APBB2 be used as a target for new drug development?

APBB2 may have some potential as a target for new drug development, but further studies and validation are needed.

Is there a link between APBB2 and other brain diseases?

There is no clear link between the APBB2 and other brain diseases, but future research may reveal more.

Does the efficacy of APBB2 change over time?

The efficacy of recombinant APBB2 protein may vary over time, possibly due to factors such as its metabolism, clearance and receptor regulation in vivo.

How to synthesize APBB2 ?

The synthesis of APBB2 usually requires the introduction of APBB2 gene into the appropriate expression system through genetic engineering technology, and then obtained through expression and purification.

Is it possible for the APBB2 to be recognized by the immune system and produce an immune response?

There may be a risk of recognition by the immune system and an immune response when treated with the APBB2, but this needs to be assessed on a case-by-case basis.

What are the possible side effects of APBB2 ?

There have been no definite reports of side effects. However, more safety assessments are needed in research and clinical applications.

Is recombinant APBB2 used in the treatment of Alzheimer's disease?

At present, there is no clear evidence that the APBB2 is used in the treatment of Alzheimer's disease, but the protein may have some potential applications in related research.

Are there other similar s with similar effects to APBB2?

There are no clear reports of similar s with similar roles to APBB2, but future studies may uncover related proteins.

Are there any drugs related to APBB2 in clinical trials?

There are no confirmed reports of drugs related to APBB2 in clinical trials, but there may be future advances in related research.

Can APBB2 be delivered through drug pathway?

APBB2 can be delivered through drug routes, such as injection, but the specific pathway needs to be further validated and optimized.

Is there no alternative to APBB2 ?

No clear replacement for the APBB2 has yet been found, but future research may reveal proteins with similar functions.

What is the estimated cost and time to develop the APBB2 ?

The estimated cost and time of developing APBB2 will involve many factors, including the strength of researchers, funds and technology, and it is difficult to give a specific estimate.

What is the scientific research value of APBB2 ?

The APBB2 can serve as an important tool for studying nervous system function and related diseases, helping to gain insight into their mechanisms and search for potential treatments.

What are the clinical applications of APBB2 ?

APBB2 has potential clinical applications in the treatment of neurosystem-related diseases, such as Alzheimer's disease.

How does APBB2 affect the function of the nervous system?

APBB2 may influence nervous system function by regulating neuronal activity and synaptic function.

Can APBB2 treat other neurosystem-related diseases?

Although recombinant APBB2 protein may have some potential in the treatment of neurosystem-related diseases, its role in the treatment of other neurosystem-related diseases needs further investigation.