Recombinant Human ARHGEF28 lysate

• Cat.No.: ARHGEF28-540HCL
• Product Overview: Over-expression cells lysed in RIPA buffer and lysate supplied in SDS loading buffer

Specification

• Source: HEK 293 cells
• Species: Human
• Molecular Mass: 69585.69Da
• Recommended Usage: WB
• Storage Instruction: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.

Gene Information

• Gene Name: ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 [ Homo sapiens ]
• Official Symbol: ARHGEF28
• Synonyms: RIP2; RGNEF; p190RHOGEF; rho guanine nucleotide exchange factor 28; p190-RhoGEF; Rho interacting protein 2; rho-guanine nucleotide exchange factor; 190 kDa guanine nucleotide exchange factor
• Gene ID: 64283
• mRNA Refseq: NM_001080479
• Protein Refseq: NP_001073948
• MIM: 612790
• UniProt ID: Q8N1W1
• Chromosome Location: 5q13.2
• Pathway: Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; EPHB-mediated forward signaling, organism-specific biosystem
• Function: RNA binding; Rho guanyl-nucleotide exchange factor activity; metal ion binding

Reviews

03/10/2022

Its high-quality standards guarantee reliable and reproducible results, enabling me to draw robust conclusions from my research.

10/04/2020

This dedication ensures that I have access to the most advanced and reliable protein in my studies, enhancing the overall quality and impact of my research outcomes.

09/25/2020

This exceptional level of support enables me to overcome challenges efficiently and progress smoothly with my research.

02/09/2020

The ARHGEF28 protein is of exceptional quality, meeting all my experimental requirements with precision and reliability.

06/02/2019

Considering the cost-effectiveness of the ARHGEF28 protein and the competitive pricing offered by the manufacturer, it aligns perfectly with my budget constraints.

07/11/2018

the ARHGEF28 protein, coupled with the manufacturer's excellent technical support, provides an ideal solution for my experimental needs.

05/02/2016

In addition to the protein's quality and technical support, the manufacturer's commitment to timely delivery and efficient supply chain management ensures that I receive the ARHGEF28 protein promptly, minimizing any potential delays in my research schedule.

04/13/2016

One of the standout advantages offered by the manufacturer is their excellent technical support.

Q&As

Is there any information available about the subcellular localization of ARHGEF28?

Limited information is available regarding the subcellular localization of ARHGEF28. It is suggested to be mainly localized in the cytoplasm, but further studies are needed to confirm and elucidate its precise subcellular localization.

Has ARHGEF28 been implicated in any developmental processes?

The involvement of ARHGEF28 in developmental processes has not been extensively studied. Future research may shed light on its potential role during development.

Has any research been conducted on the tissue distribution of ARHGEF28?

Studies on the tissue distribution of ARHGEF28 are scarce. Further investigations are required to determine its expression pattern across various tissues.

Are there any known protein interactors of ARHGEF28?

The protein interactors of ARHGEF28 have not been extensively studied. More research is needed to identify its potential interaction partners and elucidate its molecular mechanisms.

Has ARHGEF28 been investigated in any animal models or in vivo studies?

ARHGEF28 has not been extensively investigated in animal models or in vivo studies. Further research is required to explore its roles and functions in various animal models and physiological contexts.

Are there any known functional assays or experimental approaches to study ARHGEF28?

There are currently no widely established functional assays or experimental approaches specific to studying ARHGEF28. Researchers may employ a variety of techniques, such as knockdown or overexpression experiments, to assess its potential functions or roles in specific cellular processes.

Is ARHGEF28 involved in any specific physiological processes or cellular functions?

The specific physiological processes and cellular functions associated with ARHGEF28 are unknown. Further investigations are required to determine its involvement in various biological contexts.

Are there any known alternative splicing isoforms of ARHGEF28?

The existence of alternative splicing isoforms for ARHGEF28 has not been reported in current literature. However, future research may uncover the presence of alternative variants and their potential functional implications.

Has ARHGEF28 been studied in the context of neuronal development or neurodegenerative diseases?

There is currently limited information about the involvement of ARHGEF28 in neuronal development or neurodegenerative diseases. Future investigations may reveal its potential roles in these contexts.

Has ARHGEF28 been studied in non-human organisms?

Limited studies have investigated ARHGEF28 in non-human organisms. For example, one study in mice demonstrated its expression in the brain and its potential involvement in regulating dendritic spine morphology. Further research in non-human organisms may provide additional insights into the function of ARHGEF28.

Are there any diseases or conditions associated with ARHGEF28 dysregulation?

There are no known diseases or conditions specifically associated with ARHGEF28 dysregulation at present. However, with additional studies, potential links to certain diseases or conditions may be discovered.