Recombinant Human ARHGEF38 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ARHGEF38-5945H
• Product Overview: FLJ20184 MS Standard C13 and N15-labeled recombinant protein (NP_060170) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: ARHGEF38 (Rho Guanine Nucleotide Exchange Factor 38) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and p75 NTR receptor-mediated signalling. Gene Ontology (GO) annotations related to this gene include Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is DNMBP.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 25.5 kDa
• AA Sequence: MEPKEATGKENMVTKKKNLAFLRSR LYMLERRKTDTVVESSVSGDHSGTL RRSQSDRTEYNQKLQEKMTPQGECS VAETLTPEEEHHMKRMMAKREKIIK ELIQTEKDYLNDLELCVREVVQPLR NKKTDRLDVDSLFSNIESVHQISAK LLSLLEEATTDVEPAMQVIGEVFLQ IKGPLEDIYKIYCYHHDEAHSILES YEKEEELKEHLSHCIQSLKTRTRPL EQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ARHGEF38 Rho guanine nucleotide exchange factor 38 [ Homo sapiens (human) ]
• Official Symbol: ARHGEF38
• Synonyms: ARHGEF38; Rho guanine nucleotide exchange factor 38; rho guanine nucleotide exchange factor 38; Rho guanine nucleotide exchange factor (GEF) 38
• Gene ID: 54848
• mRNA Refseq: NM_017700
• Protein Refseq: NP_060170
• UniProt ID: Q9NXL2

Reviews

02/16/2021

It minimizes the risk of protein degradation and maximizes the effectiveness of the protein in various applications, such as cell signaling pathways or metabolic studies.

08/19/2019

ARHGEF38 protein may have a specific binding affinity or interaction with its target molecules or receptors, making it a valuable tool for targeted therapies or diagnostic applications.

07/29/2019

This stability is particularly advantageous for long-term studies or experiments involving extended incubation periods.

06/21/2018

Its high level of consistency allows for precise measurements and accurate data interpretation, enhancing the reliability of my findings.

05/09/2018

This collaboration can involve sharing resources, expertise, and data to advance scientific understanding and therapeutic development.

10/24/2017

In some cases, manufacturers may be open to collaborating with researchers to further investigate the applications and potential of ARHGEF38 protein.

08/05/2016

The manufacturer's deep understanding of the protein and its applications enables them to promptly and effectively address any issues that may arise during my trials.

07/02/2016

The manufacturer can offer technical expertise and guidance to researchers regarding the proper use, handling, and storage of ARHGEF38 protein.

Q&As

Are there any known interacting partners of ARHGEF38 protein?

As of now, there is no extensive information available regarding the interacting partners of ARHGEF38 protein. Identifying its interacting partners can provide insights into its regulatory mechanisms within cellular pathways.

Are there any known homologs or related proteins to ARHGEF38?

ARHGEF38 protein is a member of the larger ARHGEF family, which consists of various guanine nucleotide exchange factors. There may be homologs or related proteins within this family, but specific information about ARHGEF38 homologs is not readily available.

Can genetic variations or mutations in ARHGEF38 lead to any disorders?

Currently, there is insufficient evidence linking genetic variations or mutations in ARHGEF38 with any specific disorders or diseases. Future studies and clinical research may reveal any potential associations.

Is ARHGEF38 protein essential for normal cellular function?

The essentiality of ARHGEF38 protein for normal cellular function has not been firmly established. Further studies, including genetic knockdown or knockout experiments, are required to assess its functional importance.

Is there any literature or research available on ARHGEF38 protein?

At present, there is limited literature and research available specifically on ARHGEF38 protein. However, ongoing studies may provide more insights into its biological significance and functional characteristics.