Recombinant Human ARHGEF39 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ARHGEF39-1167H
• Product Overview: C9orf100 MS Standard C13 and N15-labeled recombinant protein (NP_116207) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: ARHGEF39 (Rho Guanine Nucleotide Exchange Factor 39) is a Protein Coding gene. Diseases associated with ARHGEF39 include Bartter Syndrome, Type 1, Antenatal and Hepatocellular Carcinoma. Among its related pathways are Signaling by GPCR and p75 NTR receptor-mediated signalling. Gene Ontology (GO) annotations related to this gene include Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is ECT2L.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 38.3 kDa
• AA Sequence: MELSCPGSRCPVQEQRARWERKRAC TARELLETERRYQEQLGLVATYFLG ILKAKGTLRPPERQALFGSWELIYG ASQELLPYLEGGCWGQGLEGFCRHL ELYNQFAANSERSQTTLQEQLKKNK GFRRFVRLQEGRPEFGGLQLQDLLP LPLQRLQQYENLVVALAENTGPNSP DHQQLTRAARLISETAQRVHTIGQK QKNDQHLRRVQALLSGRQAKGLTSG RWFLRQGWLLVVPPHGEPRPRMFFL FTDVLLMAKPRPPLHLLRSGTFACK ALYPMAQCHLSRVFGHSGGPCGGLL SLSFPHEKLLLMSTDQEELSRWYHS LTWAISSQKNTRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ARHGEF39 Rho guanine nucleotide exchange factor 39 [ Homo sapiens (human) ]
• Official Symbol: ARHGEF39
• Synonyms: ARHGEF39; Rho guanine nucleotide exchange factor 39; C9orf100; rho guanine nucleotide exchange factor 39; Rho guanine nucleotide exchange factor (GEF) 39; vav-like protein C9orf100
• Gene ID: 84904
• mRNA Refseq: NM_032818
• Protein Refseq: NP_116207
• UniProt ID: Q8N4T4

Reviews

10/10/2021

The manufacturer can provide detailed documentation on the quality control measures undertaken during protein production and purification.

01/25/2021

This can be advantageous in understanding disease mechanisms and developing novel therapeutics.

10/04/2020

the ARHGEF39 protein exhibits remarkable stability, enabling it to maintain its structural integrity and functionality throughout the experimental process.

01/16/2019

ARHGEF39 protein might have biomarker properties, meaning its levels or activity could be indicative of disease progression or treatment response.

09/03/2017

As a researcher utilizing the ARHGEF39 protein, I am fortunate to benefit from its numerous advantages in trials.

06/19/2017

the ARHGEF39 protein offers exceptional quality and purity, which is crucial for ensuring reliable and reproducible experimental outcomes.

06/21/2016

ARHGEF39 protein is highly recommended for various research applications, including ELISA and protein electron microscopy structure analysis.

05/10/2016

the manufacturer of the ARHGEF39 protein plays a vital role in supporting my research endeavors.

Q&As

Is ARHGEF39 protein essential for normal cellular function?

The essentiality of ARHGEF39 protein for normal cellular function has not been established yet. More research, including functional studies and knockdown/knockout experiments, is needed to determine its importance in cellular processes.

Can genetic variations or mutations in ARHGEF39 lead to any disorders?

There is currently no evidence linking genetic variations or mutations in ARHGEF39 to any specific disorders or diseases. Future investigations and clinical studies may reveal any potential associations.

Are there any known homologs or related proteins to ARHGEF39?

The existence of homologs or related proteins to ARHGEF39 is not well-documented. Further analysis within the ARHGEF family or related protein families may unveil any potential homologs or functional relationships.

Are there any known interacting partners of ARHGEF39 protein?

There is currently limited information on the interacting partners of ARHGEF39 protein. Identifying its binding partners can provide valuable insights into the regulatory networks in which ARHGEF39 is involved.

Is there any literature or research available on ARHGEF39 protein?

Currently, there is limited literature or research available on ARHGEF39 protein. It is an area that requires further exploration to elucidate its biological function and significance.