Recombinant Human ARMC8 protein, GST-tagged

• Cat.No.: ARMC8-831H
• Product Overview: Human ARMC8 full-length ORF ( NP_054873.2, 1 a.a. - 385 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: ARMC8 (Armadillo Repeat Containing 8) is a Protein Coding gene. Among its related pathways are Immune System. GO annotations related to this gene include binding.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 69.4 kDa
• AA Sequence: MEVTASSRHYVDRLFDPDPQKVLQG VIDMKNAVIGNNKQKANLIVLGAVP RLLYLLQQETSSTELKTECAVVLGS LAMGTENNVKSLLDCHIIPALLQGL LSPDLKFIEACLRCLRTIFTSPVTP EELLYTDATVIPHLMALLSRSRYTQ EYICQIFSHCCKGPDHQTILFNHGA VQNIAHLLTSLSYKVRMQALKCFSV LAFENPQVSMTLVNVLVDGELLPQI FVKMLQRDKPIEMQLTSAKCLTYMC RAGAIRTDDNCIVLKTLPCLVRMCS KERLLEERVEGAETLAYLIEPDVEL QRIASITDHLIAMLADYFKYPSSVS AITDIKRLDHDLKHAHELRQAAFKL YASLGANDEDIRKKVSLGEGRPPVL TASRQGVTST
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ARMC8 armadillo repeat containing 8 [ Homo sapiens ]
• Official Symbol: ARMC8
• Synonyms: ARMC8; armadillo repeat containing 8; armadillo repeat-containing protein 8; DKFZP434A043; HSPC056; S863-2; MGC4880; MGC10058
• Gene ID: 25852
• mRNA Refseq: NM_014154
• Protein Refseq: NP_054873
• UniProt ID: Q8IUR7

Reviews

12/30/2020

Great performance in ELISA.

12/14/2019

This may include options like different formulations, protein modifications, or tagging techniques. Customization can enhance the versatility of the protein and optimize its utility in the intended research.

04/06/2019

Its high purity and integrity provide the necessary assurance for consistent and reliable results, enabling me to achieve precise and meaningful outcomes in my research.

03/03/2018

The Armc8 protein demonstrates exceptional quality, making it an ideal candidate to fulfill my experimental requirements.

06/10/2017

A manufacturer can serve as a collaborative partner, engaging in discussions, and exchanging knowledge with researchers.

07/04/2016

Such support ensures researchers have access to reliable tools and expertise, facilitating their investigations into the functions, mechanisms, and disease relevance of Armc8 protein.

Q&As

Are there any known genetic disorders or conditions associated with mutations in the ARMC8 gene?

Yes, mutations in the ARMC8 gene have been linked to a condition called ciliary dyskinesia, which is characterized by respiratory tract infections and impaired movement of cilia.

Can mutations in the ARMC8 gene cause other health problems besides ciliary dyskinesia?

Currently, ciliary dyskinesia is the only known health condition associated with mutations in the ARMC8 gene. However, further research might uncover additional associations in the future.

Is the ARMC8 protein involved in any signaling pathways?

While the exact signaling pathways involving the ARMC8 protein are not fully understood, it is known to interact with other proteins involved in cell cycle regulation and microtubule organization.

Is the expression of ARMC8 protein tissue-specific?

The ARMC8 protein is expressed in multiple tissues and organs, but its levels might vary depending on the specific tissue and developmental stage.

Does the ARMC8 protein have any binding partners?

Yes, the ARMC8 protein has been shown to interact with other proteins such as dynein, which is involved in cellular transport, and beta-catenin, which is a key component of the Wnt signaling pathway.

Is there ongoing research on the ARMC8 protein?

Yes, scientists continue to investigate the role and function of the ARMC8 protein, especially in relation to ciliary dyskinesia and other cellular processes it is involved in.

Are there any known drugs or treatments targeting the ARMC8 protein?

As of now, there are no specific drugs or treatments targeting the ARMC8 protein. However, understanding its role in various cellular processes may lead to potential therapeutic interventions in the future.