Recombinant Human ARVCF, His-tagged
Cat.No. : | ARVCF-3632H |
Product Overview : | Armadillo repeat protein deleted in velo-cardio-facial syndrome (ARVCF) |
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Description : | Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein. |
Source : | E. Coli or Yeast |
Species : | Human |
Tag : | His |
Form : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Protein length : | 962 |
Purity : | >90% |
Notes : | Small volumes of ARVCF recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. |
Storage : | Store at -20 degree C. For extended storage, store at -20 or -80 degree C. |
Storage Buffer : | PBS pH 7.4, 50% glycerol |
Warning : | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Gene Name : | ARVCF armadillo repeat gene deleted in velocardiofacial syndrome [ Homo sapiens ] |
Official Symbol : | ARVCF |
Synonyms : | ARVCF; armadillo repeat gene deleted in velocardiofacial syndrome; armadillo repeat protein deleted in velo-cardio-facial syndrome; FLJ35345; |
Gene ID : | 421 |
mRNA Refseq : | NM_001670 |
Protein Refseq : | NP_001661 |
MIM : | 602269 |
UniProt ID : | O00192 |
Chromosome Location : | 22q11.21 |
Function : | protein binding; |
Products Types
◆ Recombinant Protein | ||
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Arvcf-3633M | Recombinant Mouse Arvcf, His-tagged | +Inquiry |
ARVCF-6035C | Recombinant Chicken ARVCF | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (8)
Ask a questionYes, ARVCF has been shown to interact with transcription factors and co-regulate gene expression.
Yes, ARVCF plays a role in cell-cell adhesion processes, particularly through its interaction with N-Cadherin.
Yes, the expression of the ARVCF gene is tightly regulated during development and in adult tissues.
Yes, ARVCF is important for normal heart development, and disruptions in its expression can lead to heart defects seen in VCFS.
Yes, ARVCF is involved in the Wnt signaling pathway, playing a role in the transduction of Wnt signals.
Yes, the ARVCF protein interacts with various proteins involved in cell adhesion and signaling, including N-Cadherin and β-catenin.
Yes, mutations in the ARVCF gene have been associated with the Velo-Cardio-Facial syndrome (VCFS), a genetic disorder characterized by facial abnormalities, heart defects, and learning disabilities.
No, the ARVCF protein does not possess any known enzymatic activity.
Customer Reviews (5)
Write a reviewThe Arvcf Protein's consistent stability and robust performance make it an indispensable tool for studying its multifaceted roles and mechanisms within vital biochemical pathways and cellular processes.
Its purity and efficacy make it an ideal choice for precise and accurate analysis, allowing me to generate reliable results.
By incorporating the Arvcf Protein into their studies, scientists can confidently conduct their research, ushering in groundbreaking discoveries and novel insights within their respective domains.
What truly distinguishes the Arvcf Protein is the unparalleled technical support provided by the manufacturer.
The Arvcf Protein's superior stability and functional performance render it an indispensable tool for a wide range of scientific investigations.
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