Recombinant Human ARVCF protein, GST-tagged

• Cat.No.: ARVCF-301126H
• Product Overview: Recombinant Human ARVCF (875-962 aa) protein, fused to GST tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: GST
• Form: The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8.). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization.
• Protein length: Leu875-Val962
• AA Sequence: LVDKSLEGEKTGSRDVIPMDALGPD GYSTVDQRERRPRGASSAGEASEKE PLKLDPSRKAPPPGPSRPAVRLVDA VGDAKPQPVDSWV
• Purity: 90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
• Stability: Store for up to 12 months at -20°C to -80°C as lyophilized powder.
• Storage: Short-term storage: Store at 2-8°C for (1-2 weeks).
  Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.

Gene Information

• Gene Name: ARVCF armadillo repeat gene deleted in velocardiofacial syndrome [ Homo sapiens ]
• Official Symbol: ARVCF
• Synonyms: ARVCF; armadillo repeat gene deleted in velocardiofacial syndrome; armadillo repeat protein deleted in velo-cardio-facial syndrome; FLJ35345
• Gene ID: 421
• mRNA Refseq: NM_001670
• Protein Refseq: NP_001661
• MIM: 602269
• UniProt ID: O00192

Reviews

04/27/2022

The Arvcf Protein's consistent stability and robust performance make it an indispensable tool for studying its multifaceted roles and mechanisms within vital biochemical pathways and cellular processes.

06/24/2021

Its purity and efficacy make it an ideal choice for precise and accurate analysis, allowing me to generate reliable results.

08/29/2020

By incorporating the Arvcf Protein into their studies, scientists can confidently conduct their research, ushering in groundbreaking discoveries and novel insights within their respective domains.

10/14/2016

What truly distinguishes the Arvcf Protein is the unparalleled technical support provided by the manufacturer.

04/04/2016

The Arvcf Protein's superior stability and functional performance render it an indispensable tool for a wide range of scientific investigations.

Q&As

Can ARVCF regulate gene expression?

Yes, ARVCF has been shown to interact with transcription factors and co-regulate gene expression.

Is ARVCF involved in cell adhesion?

Yes, ARVCF plays a role in cell-cell adhesion processes, particularly through its interaction with N-Cadherin.

Is the expression of the ARVCF gene regulated?

Yes, the expression of the ARVCF gene is tightly regulated during development and in adult tissues.

Can alterations in ARVCF expression affect heart development?

Yes, ARVCF is important for normal heart development, and disruptions in its expression can lead to heart defects seen in VCFS.

Does ARVCF participate in the Wnt signaling pathway?

Yes, ARVCF is involved in the Wnt signaling pathway, playing a role in the transduction of Wnt signals.

Does the ARVCF protein interact with other proteins?

Yes, the ARVCF protein interacts with various proteins involved in cell adhesion and signaling, including N-Cadherin and β-catenin.

Can mutations in the ARVCF gene lead to any disorders?

Yes, mutations in the ARVCF gene have been associated with the Velo-Cardio-Facial syndrome (VCFS), a genetic disorder characterized by facial abnormalities, heart defects, and learning disabilities.

Does the ARVCF protein have any enzymatic activity?

No, the ARVCF protein does not possess any known enzymatic activity.