Recombinant Human ASB8, His-tagged
Cat.No. : | ASB8-2341H |
Product Overview : | Recombinant human ASB8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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Description : | Ankyrin repeat and SOCS box containing 8, also known as ASB8, may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT |
Molecular Mass : | 34.0 kDa |
Protein length : | 311aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMSSSMWY IMQSIQSKYS LSERLIRTIA AIRSFPHDNV EDLIRGGADV NCTHGTLKPL HCACMVSDAD CVELLLEKGA EVNALDGYNR TALHYAAEKD EACVEVLLEY GANPNALDGN RDTPLHWAAF KNNAECVRAL LESGASVNAL DYNNDTPLSW AAMKGNLESV SILLDYGAEV RVINLIGQTP ISRLVALLVR GLGTEKEDSC FELLHRAVGH FELRKNGTMP REVARDPQLC EKLTVLCSAP GTLKTLARYA VRRSLGLQYL PDAVKGLPLP ASLKEYLLLL E |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/ml |
Gene Name : | ASB8 ankyrin repeat and SOCS box containing 8 [ Homo sapiens ] |
Official Symbol : | ASB8 |
Synonyms : | ASB8; ankyrin repeat and SOCS box containing 8; ankyrin repeat and SOCS box protein 8; FLJ21255; MGC5540; ASB-8; ankyrin repeat and SOCS box-containing 8; PP14212; |
Gene ID : | 140461 |
mRNA Refseq : | NM_024095 |
Protein Refseq : | NP_077000 |
UniProt ID : | Q9H765 |
Chromosome Location : | 12q13.12 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; |
Products Types
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ASB8-897H | Recombinant Human ASB8 protein, GST-tagged | +Inquiry |
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ASB8-424R | Recombinant Rhesus monkey ASB8 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ASB8-8659HCL | Recombinant Human ASB8 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionASB8 is known to be expressed in various tissues, including skeletal muscle, heart, and liver. It may have tissue-specific expression patterns, but more research is needed to fully understand its expression profile.
Currently, there are no known diseases directly associated with ASB8. Further investigations could reveal potential associations with certain diseases or disorders.
The regulation of ASB8 by signaling pathways or stimuli has not been extensively studied. Future research could explore any potential regulation of ASB8 expression or activity.
The specific interacting partners of ASB8 have not been extensively characterized. Further studies are required to identify proteins or molecules that interact with ASB8.
The role of ASB8 in cellular processes such as cell proliferation or differentiation is not well-defined. Additional studies are needed to determine if ASB8 is involved in these processes.
Customer Reviews (3)
Write a reviewThey are readily available to address any concerns or questions and supply valuable resources to assist in experimental design and optimization.
the manufacturer offers a wide range of ASB8 protein variants, including recombinant or native forms, as well as different conjugates and modifications.
As a researcher using ASB8 protein, I have found numerous advantages in its application during trials for various experimental purposes.
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