Recombinant Human ASB9, GST-tagged
Cat.No. : | ASB9-9921H |
Product Overview : | Recombinant Human ASB9 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | This gene encodes a member of the ankyrin repeat and suppressor of cytokine signaling (SOCS) box protein family. Members of this family can interact with the elongin B-C adapter complex via their SOCS box domain and further complex with the cullin and ring box proteins to form E3 ubiquitin ligase complexes. They may function to mediate the substrate-recognition of the E3 ubiquitin ligases. A transcribed pseudogene of this gene has been identified on chromosome 15. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-252a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | ASB9 ankyrin repeat and SOCS box containing 9 [ Homo sapiens ] |
Official Symbol : | ASB9 |
Synonyms : | ASB9; ankyrin repeat and SOCS box containing 9; ankyrin repeat and SOCS box protein 9; DKFZP564L0862; FLJ20636; MGC4954; ASB-9; ankyrin repeat and SOCS box-containing 9; ankyrin repeat and suppressor of cytokine signaling box protein 9; DKFZp564L0862; |
Gene ID : | 140462 |
mRNA Refseq : | NM_001031739 |
Protein Refseq : | NP_001026909 |
UniProt ID : | Q96DX5 |
Chromosome Location : | Xp22.2 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; |
Products Types
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ASB9-1409C | Recombinant Chicken ASB9 | +Inquiry |
ASB9-2021M | Recombinant Mouse ASB9 Protein | +Inquiry |
ASB9-898H | Recombinant Human ASB9 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
ASB9-8657HCL | Recombinant Human ASB9 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (4)
Ask a questionThe precise role of ASB9 in cellular processes such as cell proliferation or differentiation is not well-established. However, its involvement in protein degradation suggests it may influence various aspects of cellular homeostasis.
Currently, there are no specific diseases directly associated with ASB9. However, dysregulation of protein degradation pathways, in which ASB9 is involved, can contribute to various pathological conditions.
ASB9 is primarily localized in the cytoplasm of cells. However, it may also shuttle between the cytoplasm and nucleus, depending on specific cellular signaling events.
ASB9 interacts with several proteins, such as Cullin-5 (CUL5) and Elongin BC complex, to form an E3 ubiquitin-protein ligase complex. It also interacts with specific target substrates for degradation.
Customer Reviews (3)
Write a reviewIts ability to bind to negatively charged phospholipids, particularly during blood clot formation, has made it invaluable for in vitro and in vivo investigations of hemostatic mechanisms.
The manufacturer of ASB9 protein plays a crucial role in supporting my research endeavors.
the ASB9 protein is known for its strong affinity for phospholipids, particularly phosphatidylserine (PS), on the outer leaflet of cell membranes.
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