Recombinant Human ASCC3, GST-tagged

• Cat.No.: ASCC3-9924H
• Product Overview: Recombinant Human ASCC3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-111a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ASCC3 activating signal cointegrator 1 complex subunit 3 [ Homo sapiens ]
• Official Symbol: ASCC3
• Synonyms: Activating signal cointegrator 1 complex subunit 3; ASC-1 complex subunit p200; ASC-1 complex subunit p200-KD subunit; ASC1p200; ascc3; ATP binding 1; B630009I04Rik; dJ121G13.4; DJ467N11.1; HELC1_HUMAN; HELIC1; Helicase; helicase, ATP binding 1; p200; RNA helicase family; RNAH; RP1-121G13.4; Trip4 complex subunit p200; ASCC3
• Gene ID: 10973
• mRNA Refseq: NM_022091.3
• Protein Refseq: NP_071374.1
• MIM: 614217
• UniProt ID: Q8N3C0
• Chromosome Location: 6q16
• Function: ATP binding; ATP-dependent 3-5 DNA helicase activity; nucleic acid binding; protein binding

Reviews

11/14/2022

manufacturers often have a wealth of knowledge and expertise in the field of Ascc3 protein research.

10/22/2020

the manufacturer can assist in sourcing complementary reagents and tools, such as specific antibodies or detection systems, to complement the use of Ascc3 protein in trials.

06/03/2019

They can offer specialized formulations, concentrations, or modifications of Ascc3 protein to suit unique experimental requirements.

Q&As

Does Ascc3 have any impact on cellular metabolism?

The direct impact of Ascc3 on cellular metabolism is not well-documented. However, given its role in transcriptional regulation, it may indirectly influence metabolic processes by controlling gene expression.

Is Ascc3 involved in DNA repair processes?

Ascc3 is known to be involved in DNA repair processes as part of the ASC-1 complex. It contributes to the repair of DNA double-strand breaks, promoting genome stability.

How is Ascc3 localized within the cell?

Ascc3 is primarily localized in the nucleus, where it carries out its functions in gene expression regulation.

Does Ascc3 undergo any post-translational modifications?

The post-translational modifications of Ascc3 have not been extensively studied. However, it is possible that Ascc3 may undergo modifications such as phosphorylation or acetylation, which can regulate its activity.

Can Ascc3 be targeted for therapeutic interventions or drug discovery?

Due to the limited understanding of Ascc3's specific role in diseases, it is currently uncertain if it can be directly targeted for therapeutic interventions or drug discovery.

Is there any association between Ascc3 and human diseases?

Currently, there are no known human diseases directly associated with Ascc3. However, dysregulation of transcriptional coactivation complexes, in which Ascc3 is involved, can contribute to various diseases.