ASCC3
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Official Full Name
ASCC3 activating signal cointegrator 1 complex subunit 3 [ Homo sapiens ]
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Synonyms
Ascc3; activating signal cointegrator 1 complex subunit 3; helicase, ATP binding 1;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- E.coli
- E.Coli or Yeast
- HEK293
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | ASCC3-9924H | Recombinant Human ASCC3, GST-tagged | E.coli | GST | 1-111a.a. | |
Human | ASCC3-9925H | Recombinant Human ASCC3, His-tagged | E.coli | His | 1812-2176aa | |
Mouse | ASCC3-2024M | Recombinant Mouse ASCC3 Protein | Mammalian Cell | His | ||
Mouse | ASCC3-783M | Recombinant Mouse ASCC3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | ASCC3-783M-B | Recombinant Mouse ASCC3 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | Ascc3-3113R | Recombinant Rat Ascc3, His-tagged | E.Coli or Yeast | His | 2197 | |
Chicken | ASCC3-3112C | Recombinant Chicken ASCC3, His-tagged | E.Coli or Yeast | His | 2211 |
- Involved Pathway
- Protein Function
- Interacting Protein
ASCC3 involved in several pathways and played different roles in them. We selected most pathways ASCC3 participated on our site, such as ALKBH3 mediated reversal of alkylation damage, DNA Damage Reversal, DNA Repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASCC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
ALKBH3 mediated reversal of alkylation damage | ASCC1;ALKBH3;ASCC3;ASCC2 |
DNA Damage Reversal | ASCC2;ASCC3;ALKBH3;ASCC1;MGMT;ALKBH2 |
DNA Repair | MGMT;MCRS1;COPS6;RNF111;RAD9A;RAD9B;PPP4CA;EME2;ACTL6A |
Reversal of alkylation damage by DNA dioxygenases | ASCC2;ALKBH3;ASCC1;ASCC3;ALKBH2 |
ASCC3 has several biochemical functions, for example, ATP binding, ATP-dependent 3-5 DNA helicase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ASCC3 itself. We selected most functions ASCC3 had, and list some proteins which have the same functions with ASCC3. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
ATP binding | PPP1CA;CHORDC1;MCM3;STK32A;PET112L;DDX19A;TTBK2;ATP2A2B;PIK3C2G |
ATP-dependent 3-5 DNA helicase activity | ASCC3;WRN;BLM;RECQL4 |
poly(A) RNA binding | CHTOP;HNRPLL;MRPL32;NQO1;LARP1;RPL3;HIST1H4J;SPATS2L;RPL22 |
protein binding | PIF1;SID4;IPO5;Rhox5;FANCG;KIAA0649;PSMA5;CHORDC1;SKI |
ASCC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASCC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASCC3.
EIF3H; G3BP1; OTUD6B; G3BP2; SKIL; spoVID; ssrna_ug; Srp72; CDK1; IQGAP1; SUMO3; Rpl35; Rrbp1
- Q&As
- Reviews
Q&As (6)
Ask a questionThe direct impact of Ascc3 on cellular metabolism is not well-documented. However, given its role in transcriptional regulation, it may indirectly influence metabolic processes by controlling gene expression.
Ascc3 is known to be involved in DNA repair processes as part of the ASC-1 complex. It contributes to the repair of DNA double-strand breaks, promoting genome stability.
Ascc3 is primarily localized in the nucleus, where it carries out its functions in gene expression regulation.
The post-translational modifications of Ascc3 have not been extensively studied. However, it is possible that Ascc3 may undergo modifications such as phosphorylation or acetylation, which can regulate its activity.
Due to the limited understanding of Ascc3's specific role in diseases, it is currently uncertain if it can be directly targeted for therapeutic interventions or drug discovery.
Currently, there are no known human diseases directly associated with Ascc3. However, dysregulation of transcriptional coactivation complexes, in which Ascc3 is involved, can contribute to various diseases.
Customer Reviews (3)
Write a reviewmanufacturers often have a wealth of knowledge and expertise in the field of Ascc3 protein research.
the manufacturer can assist in sourcing complementary reagents and tools, such as specific antibodies or detection systems, to complement the use of Ascc3 protein in trials.
They can offer specialized formulations, concentrations, or modifications of Ascc3 protein to suit unique experimental requirements.
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