Recombinant Human ASCL2 Protein Pre-coupled Magnetic Beads

• Cat.No.: ASCL2-387H-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Human
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: ASCL2 achaete-scute family bHLH transcription factor 2 [ Homo sapiens (human) ]
• Official Symbol: ASCL2
• Synonyms: ASH2; HASH2; MASH2; bHLHa45
• Gene ID: 430
• mRNA Refseq: NM_005170.3
• Protein Refseq: NP_005161.1
• MIM: 601886
• UniProt ID: Q99929

Reviews

06/08/2022

The manufacturer's commitment to providing excellent technical support is highly valuable.

05/02/2018

The combination of high-quality ASCL2 protein and excellent technical support provided by the manufacturer makes them the ideal choice for my research.

07/15/2017

The ASCL2 protein offered by the manufacturer is of exceptional quality, and it meets the rigorous standards necessary for my experimental needs.

Q&As

Can ASCL2 induce pluripotency or cellular reprogramming?

ASCL2, along with other transcription factors and signaling molecules, has been used in combination to induce cellular reprogramming and pluripotency in certain contexts, demonstrating its ability to alter cell fate.

Does ASCL2 have any role in other tissues or organs?

ASCL2's primary role is in the gastrointestinal tract, but it may also have roles in other tissues and organs during development, including lung and pancreas.

Are there any known interacting partners of ASCL2?

ASCL2 interacts with various co-factors and proteins involved in stem cell regulation and development, including β-catenin, POU5F1 (Oct4), and SMAD proteins.

Is ASCL2 essential for the development of the gastrointestinal tract?

Yes, ASCL2 is crucial for the normal development of the gastrointestinal tract, particularly in regulating the differentiation and proliferation of intestinal stem cells.

Can ASCL2 be targeted for therapeutic interventions or drug discovery?

ASCL2 is being explored as a potential therapeutic target for colorectal cancer due to its involvement in promoting abnormal cell proliferation. Targeting ASCL2 may help inhibit tumor growth and progression.

How does ASCL2 regulate intestinal stem cells?

ASCL2 promotes the self-renewal of intestinal stem cells by activating specific gene expression programs involved in stem cell maintenance. It also regulates the balance between proliferation and differentiation of these cells.