Recombinant Human aTRX protein, His-tagged
Cat.No. : | aTRX-1288H |
Product Overview : | Recombinant Human aTRX protein(Trp221~Ser342), fused with N-terminal His Tag, was expressed in E.coli. |
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Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Molecular Mass : | 18kDa |
Protein Length : | Trp221~Ser342 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 95% |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Reconstitution : | Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | ATRX alpha thalassemia/mental retardation syndrome X-linked [ Homo sapiens ] |
Official Symbol : | aTRX |
Synonyms : | ATRX; alpha thalassemia/mental retardation syndrome X-linked; alpha thalassemia/mental retardation syndrome X linked (RAD54 (S. cerevisiae) homolog) , JMS, Juberg Marsidi syndrome , RAD54; transcriptional regulator ATRX; RAD54 homolog (S. cerevisiae); XH2; XNP; RAD54 homolog; X-linked helicase II; Zinc finger helicase; helicase 2, X-linked; X-linked nuclear protein; ATP-dependent helicase ATRX; DNA dependent ATPase and helicase; alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae); JMS; SHS; ATR2; SFM1; RAD54; MRXHF1; RAD54L; ZNF-HX; MGC2094; |
Gene ID : | 546 |
mRNA Refseq : | NM_000489 |
Protein Refseq : | NP_000480 |
MIM : | 300032 |
UniProt ID : | P46100 |
Products Types
◆ Recombinant Protein | ||
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ATRX-1289H | Recombinant Human ATRX protein, His-SUMO-tagged | +Inquiry |
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ATRX-2191M | Recombinant Mouse ATRX Protein | +Inquiry |
◆ Lysates | ||
ATRX-150HCL | Recombinant Human ATRX cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe research on ATRX gene mainly focuses on its function and regulatory mechanism, and its relationship with genetic diseases and cancer. So far, several important findings on ATRX gene function and regulation have been made.
Yes, ATRX gene expression is affected by a variety of regulatory factors, including transcription factor binding, DNA methylation status, etc. These regulatory mechanisms ensure the adaptability and stability of the ATRX gene.
ATRX gene mutation can lead to Alpha thalassemia/mental retardation syndrome X-linked. The main features of this syndrome include mental retardation, developmental delay, craniofacial deformity, anemia, etc.
ATRX gene is widely expressed in human body, but its expression level may vary in different tissues and organs. Its expression is higher in brain, kidney, muscle and other tissues.
ATRX genes may interact with other genes related to chromatin structure and DNA repair. For example, ATRX interacts with Death-domain associated protein (DAXX) to participate in chromatin repair and regulation.
Yes, the ATRX gene is involved in the regulation of DNA repair. Together with other proteins, it maintains the normal progression of DNA repair by maintaining chromatin structure and regulating gene expression.
Customer Reviews (3)
Write a reviewThe purity of ATRX is very high, which can ensure the reliability of the experimental results and also facilitate the subsequent experimental operation.
ATRX is really amazing. The results of every experiment are very consistent, which shows that its production process is very careful.
This band positions of ATRX in Western blot were accurate and showed good specificity.
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