Recombinant Human BRAF Protein, Full Length, GST tagged
Cat.No. : | BRAF-12HFL |
Product Overview : | Recombinant Human BRAF protein (Full Length) with GST tag was expressed in insect cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. |
Source : | Insect cells |
Species : | Human |
Tag : | GST |
Protein length : | Full Length |
Form : | Liquid |
Molecular Mass : | 113.6 kDa |
Applications : | Kinase Assay (KA) |
Storage : | At -80 centigrade, Avoid Freeze/Thaw Cycles |
Storage Buffer : | 50mM tris, pH 7.5, with 50% glycerol, 0.02% Triton X-100, 150mM NaCl, 0.5mM EDTA, 2mM DTT |
Shipping : | Dry ice |
Gene Name : | BRAF B-Raf proto-oncogene, serine/threonine kinase [ Homo sapiens (human) ] |
Official Symbol : | BRAF |
Synonyms : | BRAF; B-Raf proto-oncogene, serine/threonine kinase; NS7; B-raf; BRAF1; RAFB1; B-RAF1; BRAF-1; serine/threonine-protein kinase B-raf; 94 kDa B-raf protein; B-Raf proto-oncogene serine/threonine-protein kinase (p94); B-Raf serine/threonine-protein; murine sarcoma viral (v-raf) oncogene homolog B1; proto-oncogene B-Raf; v-raf murine sarcoma viral oncogene homolog B; v-raf murine sarcoma viral oncogene homolog B1; EC 2.7.11.1 |
Gene ID : | 673 |
mRNA Refseq : | NM_004333 |
Protein Refseq : | NP_004324 |
MIM : | 164757 |
UniProt ID : | P15056 |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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