Description : |
This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants. |
Source : |
Wheat Germ |
Species : |
Human |
Tag : |
GST |
Form : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : |
97.13 kDa |
AA Sequence : |
MGKKHKKHKSDKHLYEEYVEKPLKL VLKVGGNEVTELSTGSSGHDSSLFE DKNDHDKHKDRKRKKRKKGEKQIPG EEKGRKRRRVKEDKKKRDRDRVENE AEKDLQCHAPVRLDLPPEKPLTSSL AKQEEVEQTPLQEALNQLMRQLQRK DPSAFFSFPVTDFIAPGYSMIIKHP MDFSTMKEKIKNNDYQSIEELKDNF KLMCTNAMIYNKPETIYYKAAKKLL HSGMKILSQERIQSLKQSIDFMADL QKTRKQKDGTDTSQSGEDGGCWQRE REDSGDAEAHAFKSPSKENKKKDKD MLEDKFKSNNLEREQEQLDRIVKES GGKLTRRLVNSQCEFERRKPDGTTT LGLLHPVDPIVGEPGYCPVRLGMTT GRLQSGVNTLQGFKEDKRNKVTPVL YLNYGPYSSYAPHYDSTFANISKDD SDLIYSTYGEDSDLPSDFSIHEFLA TCQDYPYVMADSLLDVLTKGGHSRT LQEMEMSLPEDEGHTRTLDTAKEME ITEVEPPGRLDSSTQDRLIALKAVT NFGVPVEVFDSEEAEIFQKKLDETT RLLRELQEAQNERLSTRPPPNMICL LGPSYREMHLAEQVTNNLKELAQQV TPGDIVSTYGVRKAMGISIPSPVME NNFVDLTEDTEEPKKTDVAECGPGG S |
Applications : |
Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : |
Best use within three months from the date of receipt of this protein. |
Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |