Recombinant Mouse Brd7 Protein, Myc/DDK-tagged
Cat.No. : | Brd7-1890M |
Product Overview : | Purified recombinant protein of mouse full-length bromodomain containing 7 (Brd7), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 74.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Brd7 bromodomain containing 7 [ Mus musculus (house mouse) ] |
Official Symbol : | Brd7 |
Synonyms : | BRD7; bromodomain containing 7; bromodomain-containing protein 7; bromodomain-containing 7; 75 kDa bromodomain protein; bromodomain protein 75 kDa; protein tyrosine phosphatase, non-receptor type 13 interacting protein; BP75; CELTIX1; Ptpn13ip |
Gene ID : | 26992 |
mRNA Refseq : | NM_012047 |
Protein Refseq : | NP_036177 |
UniProt ID : | O88665 |
Products Types
◆ Recombinant Protein | ||
BRD7-1086M | Recombinant Mouse BRD7 Protein, His (Fc)-Avi-tagged | +Inquiry |
BRD7-13H | Recombinant Human BRD7, GST-tagged | +Inquiry |
BRD7-12545Z | Recombinant Zebrafish BRD7 | +Inquiry |
BRD7-14H | Recombinant Human BRD7, GST-tagged | +Inquiry |
BRD7-12H | Recombinant Human BRD7, GST-tagged | +Inquiry |
◆ Lysates | ||
BRD7-8411HCL | Recombinant Human BRD7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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