Recombinant Human Caspase 5, Apoptosis-related Cysteine Peptidase
Cat.No. : | CASP5-600H |
Product Overview : | Recombinant Human CASP5 was produced inE. coli. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CASP5-600H |
Description : | Caspase 5 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. It is an inflammatory caspase, along with caspase 1, caspase 4 and the murine caspase 4 homolog caspase 11, and has a role in the immune system. |
Source : | E. coli. |
Purity : | ≥95% (SDS-PAGE). |
Formulation : | Lyophilized. |
Reconstitution : | Reconstitute to 1U/µl with PBS containing 15% glycerol. |
Specific Activity : | ~5"000U/mg protein. One unit is defined as the amount of enzyme that cleaves 1nmol of the caspase substrate WEHD-pNA per hour at 37°C in a reaction solution containing 50mM HEPES, pH 7.2, 50mM NaCl, 0.1% CHAPS, 10mM EDTA, 5% glycerol and 10mM DTT. |
Application : | In combination with caspase-5 activity assays, the enzyme is useful in screening caspase inhibitors, studying enzyme regulation and kinetics, determining target substrate or as a positive control in caspase-5 activity assays. We recommend using 1 unit per assay for analyzing caspase activity. |
Storage : | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. |
Gene Name : | CASP5 caspase 5, apoptosis-related cysteine peptidase [ Homo sapiens ] |
Synonyms : | CASP5; caspase 5, apoptosis-related cysteine peptidase; ICH-3; MGC141966; ICEREL-III; ICE(rel)III; caspase-5; CASP-5; TY protease; protease TY; ICE(rel)-III; protease ICH-3; EC 3.4.22.58; Caspase-5 subunit p20; Caspase-5 subunit p10; caspase 5, apoptosis-related cysteine protease |
Gene ID : | 838 |
mRNA Refseq : | NM_001136109 |
Protein Refseq : | NP_001129581 |
MIM : | 602665 |
UniProt ID : | P51878 |
Chromosome Location : | 11q22.2-q22.3 |
Pathway : | NOD-like receptor signaling pathway |
Function : | cysteine-type endopeptidase activity; cysteine-type peptidase activity; peptidase activity; protein binding |
Products Types
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◆ Lysates | ||
CASP5-7835HCL | Recombinant Human CASP5 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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