Recombinant Human CAST
Cat.No. : | CAST-27403TH |
Product Overview : | Recombinant full length corresponding to amino acids 1-686 of Human Calpastatin with a proprietary tag; predicited MWt 101.3kDa inclusive of tag. |
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Description : | The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. |
Protein length : | 686 amino acids |
Molecular Weight : | 101.530kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.31% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MNPTETKAVKTEPEKKSQSTKLSVV HEKKSQEGKPKEHTEPKSLPKQASD TGSNDAHNKKAVSRSAEQQPSEKST EPKTKPQDMISAGGESVAGITAISG KPGDKKKEKKSLTPAVPVESKPDKP SGKSGMDAALDDLIDTLGGPEETEE ENTTYTGPEVSDPMSSTYIEELGKR EVTIPPKYRELLAKKEGITGPPADS SKPIGPDDAIDALSSDFTCGSPTAA GKKTEKEESTEVLKAQSAGTVRSAA PPQEKKRKVEKDTMSDQALEALSAS LGTRQAEPELDLRSIKEVDEAKAKE EKLEKCGEDDETIPSEYRLKPATDK DGKPLLPEPEEKPKPRSESELIDEL SEDFDRSECKEKPSKPTEKTEESKA AAPAPVSEAVCRTSMCSIQSAPPEP ATLKGTVPDDAVEALADSLGKKEAD PEDGKPVMDKVKEKAKEEDREKLGE KEETIPPDYRLEEVKDKDGKPLLPK ESKEQLPPMSEDFLLDALSEDFSGP QNASSLKFEDAKLAAAISEVVSQTP ASTTQAGAPPRDTSQSDKDLDDALD KLSDSLGQRQPDPDENKPMEDKVKE KAKAEHRDKLGERDDTIPPEYRHLL DDNGQDKPVKPPTKKSEDSKKPADD QDPIDALSGDLDSCPSTTETSQNTA KDKCKKAASSSKAPKNGGKAKDSAK TTEETSKPKDD |
Sequence Similarities : | Belongs to the protease inhibitor I27 (calpastatin) family. |
Gene Name : | CAST calpastatin [ Homo sapiens ] |
Official Symbol : | CAST |
Synonyms : | CAST; calpastatin; |
Gene ID : | 831 |
mRNA Refseq : | NM_001042440 |
Protein Refseq : | NP_001035905 |
MIM : | 114090 |
Uniprot ID : | P20810 |
Chromosome Location : | 5q14-q22 |
Function : | calcium-dependent cysteine-type endopeptidase inhibitor activity; endopeptidase inhibitor activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
CAST-1350H | Recombinant Human CAST Protein (1-667 aa), His-tagged | +Inquiry |
CAST-628H | Recombinant Human CAST Protein, His&GST-tagged | +Inquiry |
CAST-807R | Recombinant Rat CAST Protein, His (Fc)-Avi-tagged | +Inquiry |
Cast-776M | Recombinant Mouse Cast Protein, MYC/DDK-tagged | +Inquiry |
CAST-0441H | Recombinant Human CAST Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
CAST-7824HCL | Recombinant Human CAST 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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