Recombinant Human CCR7 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | CCR7-4640H |
Product Overview : | CCR7 MS Standard C13 and N15-labeled recombinant protein (NP_001829) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 42.9 kDa |
AA Sequence : | MDLGKPMKSVLVVALLVIFQVCLCQ DEVTDDYIGDNTTVDYTLFESLCSK KDVRNFKAWFLPIMYSIICFVGLLG NGLVVLTYIYFKRLKTMTDTYLLNL AVADILFLLTLPFWAYSAAKSWVFG VHFCKLIFAIYKMSFFSGMLLLLCI SIDRYVAIVQAVSAHRHRARVLLIS KLSCVGIWILATVLSIPELLYSDLQ RSSSEQAMRCSLITEHVEAFITIQV AQMVIGFLVPLLAMSFCYLVIIRTL LQARNFERNKAIKVIIAVVVVFIVF QLPYNGVVLAQTVANFNITSSTCEL SKQLNIAYDVTYSLACVRCCVNPFL YAFIGVKFRNDLFKLFKDLGCLSQE QLRQWSSCRHIRRSSMSVEAETTTT FSPTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | CCR7 C-C motif chemokine receptor 7 [ Homo sapiens (human) ] |
Official Symbol : | CCR7 |
Synonyms : | CCR7; chemokine (C-C motif) receptor 7; CMKBR7, EBI1; C-C chemokine receptor type 7; BLR2; CD197; CDw197; CCR-7; CC-CKR-7; C-C CKR-7; MIP-3 beta receptor; CC chemokine receptor 7; chemokine (C-C) receptor 7; Epstein-Barr virus induced gene 1; EBV-induced G protein-coupled receptor 1; EBV-induced G-protein coupled receptor 1; Epstein-Barr virus induced G-protein coupled receptor; lymphocyte-specific G protein-coupled peptide receptor; epstein-Barr virus-induced G-protein coupled receptor 1; EBI1; CMKBR7; |
Gene ID : | 1236 |
mRNA Refseq : | NM_001838 |
Protein Refseq : | NP_001829 |
MIM : | 600242 |
UniProt ID : | P32248 |
Products Types
◆ Recombinant Protein | ||
CCR7-645H | Recombinant Human CCR7 Protein, His-tagged | +Inquiry |
Ccr7-906M | Recombinant Mouse Ccr7 Protein, MYC/DDK-tagged | +Inquiry |
CCR7-537R | Recombinant Rhesus Macaque CCR7 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ccr7-646M | Recombinant Mouse Ccr7 Protein, His-tagged | +Inquiry |
CCR7-0696H | Recombinant Human CCR7 Protein | +Inquiry |
◆ Assay kits | ||
Kit-1159 | CCR7 HEK 293 β-Arrestin GPCR Assay Kit | +Inquiry |
Kit-1160 | CCR7 CHO-K1 β-Arrestin GPCR Assay Kit | +Inquiry |
Kit-1161 | cAMP CCR7 CHO-K1 GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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