Recombinant Human CDK1 protein, T7/His-tagged

• Cat.No.: CDK1-213H
• Product Overview: Recombinant human CDK1 cDNA (297aa, Isoform-1) fused with T7-His-TEV cleavage site Tag at N-terminal was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: T7/His
• Form: 1.0 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, Sucrose and DTT.
• AA Sequence: MASMTGGQQMGRGHHHHHHGNLYFQ GGEFEDYTKIEKIGEGTYGVVYKGR HKTTGQVVAMKKIRLESEEEGVPST AIREISLLKELRHPNIVSLQDVLMQ DSRLYLIFEFLSMDLKKYLDSIPPG QYMDSSLVKSYLYQILQGIVFCHSR RVLHRDLKPQNLLIDDKGTIKLADF GLARAFGIPIRVYTHEVVTLWYRSP EVLLGSARYSTPVDIWSIGTIFAEL ATKKPLFHGDSEIDQLFRIFRALGT PNNEVWPEVESLQDYKNTFPKWKPG SLASHVKNLDENGLDLLSKMLIYDP AKRISGKMALNHPYFNDLDNQIKKM
• Purity: >90% by SDS-PAGE
• Storage: Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 7 days.

Gene Information

• Gene Name: CDK1 cyclin-dependent kinase 1 [ Homo sapiens ]
• Official Symbol: CDK1
• Synonyms: CDK1; cyclin-dependent kinase 1; CDC2, cell division cycle 2, G1 to S and G2 to M; CDC28A; p34 protein kinase; cell cycle controller CDC2; cell division protein kinase 1; cell division control protein 2 homolog; cell division cycle 2, G1 to S and G2 to M; CDC2; P34CDC2; MGC111195; DKFZp686L20222
• Gene ID: 983
• mRNA Refseq: NM_001170406
• Protein Refseq: NP_001163877
• MIM: 116940
• UniProt ID: P06493
• Chromosome Location: 10q21.2
• Pathway: APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Cyclin B, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; ARMS-mediated activation, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem
• Function: ATP binding; Hsp70 protein binding; RNA polymerase II carboxy-terminal domain kinase activity; cyclin binding; cyclin-dependent protein kinase activity; cyclin-dependent protein kinase activity; histone kinase activity; nucleotide binding; protein binding

Reviews

01/30/2023

The product brochure is very detailed and has comprehensive basic information about the CDK1 protein.

11/09/2022

The staff actively communicated with me and solved many technical problems.

10/18/2022

Very professional customer service, fully understanding the needs of the customer and giving professional advice.

Q&As

What diseases is CDK1 involved in?

CDK1 is involved in papillary thyroid cancer, hepatocellular carcinoma, and other diseases.

How does CDK1 relate to IL-33 expression?

CDK1 is positively correlated with IL⁃33 expression and CDK1 and IL⁃33 expression interact with each other.

What is the function of CDK1?

CDK1 is an important regulator of the eukaryotic cell cycle that drives cell cycle progression by binding to cell cycle proteins.

What is the expression level of CDK1 in colorectal cancer?

CDK1 expression levels were higher in CRC tissues than in paracancerous tissues.