Recombinant Human CDK19 Protein, GST-tagged

• Cat.No.: CDK19-5145H
• Product Overview: Human CDC2L6 full-length ORF ( NP_055891.1, 1 a.a. - 502 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 83.2 kDa
• AA Sequence: MDYDFKAKLAAERERVEDLFEYEGC KVGRGTYGHVYKARRKDGKDEKEYA LKQIEGTGISMSACREIALLRELKH PNVIALQKVFLSHSDRKVWLLFDYA EHDLWHIIKFHRASKANKKPMQLPR SMVKSLLYQILDGIHYLHANWVLHR DLKPANILVMGEGPERGRVKIADMG FARLFNSPLKPLADLDPVVVTFWYR APELLLGARHYTKAIDIWAIGCIFA ELLTSEPIFHCRQEDIKTSNPFHHD QLDRIFSVMGFPADKDWEDIRKMPE YPTLQKDFRRTTYANSSLIKYMEKH KVKPDSKVFLLLQKLLTMDPTKRIT SEQALQDPYFQEDPLPTLDVFAGCQ IPYPKREFLNEDDPEEKGDKNQQQQ QNQHQQPTAPPQQAAAPPQAPPPQQ NSTQTNGTAGGAGAGVGGTGAGLQH SQDSSLNQVPPNKKPRLGPSGANSG GPVMPSDYQHSSSRLNYQSSVQGSS QSQSTLGYSSSSQQSSQYHPSHQAH RY
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CDK19 cyclin dependent kinase 19 [ Homo sapiens (human) ]
• Official Symbol: CDK19
• Synonyms: CDC2L6; CDK19; cyclin dependent kinase 19; CDK11; CDC2L6; bA346C16.3; cyclin-dependent kinase 19; CDC2-related protein kinase 6; CDK8-like cyclin-dependent kinase; cell division cycle 2-like 6 (CDK8-like); cell division cycle 2-like protein kinase 6; cell division protein kinase 19; cyclin dependent kinase 19 variant 2; cyclin-dependent kinase (CDC2-like) 11; cyclin-dependent kinase 11; death-preventing kinase; EC 2.7.11.22
• Gene ID: 23097
• mRNA Refseq: NM_001300960
• Protein Refseq: NP_001287889
• MIM: 614720
• UniProt ID: Q9BWU1