Recombinant Human CDK2AP1, His-tagged
Cat.No. : | CDK2AP1-1936H |
Product Overview : | Recombinant CDK2AP1 protein fused to his-tag was expressed inE.coliand purified by using conventional chromatography techniques. 16.6kDa (152aa). |
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Cat. No. : | CDK2AP1-1936H |
Description : | CDK2AP1 is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. Also, interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes. |
Source : | E.coli. |
Purity : | > 95% by SDS – PAGE. |
Physical Appearance : | Liquid. |
Formulation : | 20mM Tris-HCl buffer (pH8.0) containing 50% glycerol, 2mM DTT. |
Concentration : | 0.25 mg/ml (determined by Bradford assay). |
Sequences Of Amino Acids : | MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSY KPNLAA H MPA AALNAAGSVH SPSTSMATSS QYRQLLSDYG PPSLGYT QGTGNS QV P Q S KY AELLAIIEEL GKEIRPTYAG SKSAMERLKR GIIHARGLVR ECLAET ERNA R S. |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | CDK2AP1 cyclin-dependent kinase 2 associated protein 1 [ Homo sapiens ] |
Synonyms : | CDK2AP1; cyclin-dependent kinase 2 associated protein 1; DOC1; ST19; DORC1; doc-1; p12DOC-1; CDK2-associated protein 1; Deleted in oral cancer-1; deleted in oral cancer 1; putative oral cancer suppressor; cyclin-dependent kinase 2-associated protein 1; CDKAP1 |
Gene ID : | 8099 |
mRNA Refseq : | NM_004642 |
Protein Refseq : | NP_004633 |
MIM : | 602198 |
UniProt ID : | O14519 |
Chromosome Location : | 12q24.31 |
Function : | DNA binding; protein binding |
Products Types
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Cdk2ap1-2088M | Recombinant Mouse Cdk2ap1 Protein, Myc/DDK-tagged | +Inquiry |
CDK2AP1-11047H | Recombinant Human CDK2AP1, GST-tagged | +Inquiry |
CDK2AP1-0977H | Recombinant Human CDK2AP1 Protein (Met1-Ser115), C-His tagged | +Inquiry |
◆ Lysates | ||
CDK2AP1-7628HCL | Recombinant Human CDK2AP1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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