Recombinant Human CDK4 protein, GST-tagged
Cat.No. : | CDK4-758H |
Product Overview : | Recombinant Human CDK4 protein(NP_000066.1)(Met1-Glu303), fused with GST tag, was expressed in Insect Cells. |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
- Download
Source : | Insect Cells |
Species : | Human |
Tag : | GST |
Form : | Lyophilized from sterile 50mM Tris, 100mM NaCl, 10% gly, 0.5mM PMSF, pH 8.0Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : | The recombinant human CDK4/GST chimera consists of 528 amino acids and predicts a molecular mass of 60 kDa. It migrates as an approximately 55 kDa band in SDS-PAGE under reducing conditions. |
Protein Length : | Met1-Glu303 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 80 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | CDK4 cyclin-dependent kinase 4 [ Homo sapiens ] |
Official Symbol : | CDK4 |
Synonyms : | CDK4; cyclin-dependent kinase 4; PSK J3; cell division protein kinase 4; CMM3; PSK-J3; MGC14458; |
Gene ID : | 1019 |
mRNA Refseq : | NM_000075 |
Protein Refseq : | NP_000066 |
MIM : | 123829 |
UniProt ID : | P11802 |
Products Types
◆ Recombinant Protein | ||
CDK4-633H | Recombinant Human CDK4 Protein, GST-tagged | +Inquiry |
CDK4-962R | Recombinant Rat CDK4 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDK4-3139H | Recombinant Human CDK4 Protein, MYC/DDK-tagged | +Inquiry |
CDK4-1525M | Recombinant Mouse CDK4 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDK4-1016H | Active Recombinant Human CDK4 Protein, His-Tagged | +Inquiry |
◆ Lysates | ||
CDK4-664HCL | Recombinant Human CDK4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionResistance to CDK4 inhibitors and the need for patient stratification are some of the challenges in using CDK4 as a therapeutic target.
Yes, CDK4 is a target for cancer therapy, and drugs that inhibit CDK4 have been developed for the treatment of specific cancers.
CDK4 is clinically relevant because it plays a crucial role in the development and progression of various cancers.
CDK4 overactivity is commonly associated with breast cancer, melanoma, and liposarcoma.
CDK4 can promote cell senescence, a state of irreversible growth arrest, which has implications in cancer therapy.
Customer Reviews (3)
Write a reviewWhether it's troubleshooting experimental issues, providing guidance on experimental design, or answering any inquiries related to the CDK4 protein, the manufacturer is committed to helping researchers overcome challenges and achieve their scientific goals.
They actively seek feedback and incorporate it into their product development process, continuously improving the quality and performance of the CDK4 protein.
The manufacturer also values customer satisfaction and strives to maintain a strong relationship with researchers.
Ask a Question for All CDK4 Products
Required fields are marked with *
My Review for All CDK4 Products
Required fields are marked with *
Inquiry Basket