Recombinant Human CHRM4 Protein, His-tagged, OVA Conjugated

• Cat.No.: CHRM4-2786H
• Product Overview: OVA Conjugated Recombinant Human CHRM4 Protein (Pro258-Glu273) fused with a N-His tag.

Specification

• Description: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition.
• Source: Protein Conjugation
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 16 kDa
• Protein length: Pro258-Glu273
• Purity: > 90%
• Applications: Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: CHRM4 cholinergic receptor, muscarinic 4 [ Homo sapiens ]
• Official Symbol: CHRM4
• Synonyms: CHRM4; cholinergic receptor, muscarinic 4; muscarinic acetylcholine receptor M4; acetylcholine receptor; muscarinic 4; acetylcholine receptor, muscarinic 4; HM4; M4R
• Gene ID: 1132
• mRNA Refseq: NM_000741
• Protein Refseq: NP_000732
• MIM: 118495
• UniProt ID: P08173