Recombinant Human CREB1 Protein (Lys136-Asp341), His tagged

• Cat.No.: CREB1-1803H
• Product Overview: Recombinant human CREB (Lys136-Asp341) fused with His tag was expressed in E. coli.

Specification

• Description: Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 22.96 kDa
• Protein Length: Lys136-Asp341
• Purity: >90% as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: CREB1 cAMP responsive element binding protein 1 [ Homo sapiens (human) ]
• Official Symbol: CREB1
• Synonyms: CREB1; cAMP responsive element binding protein 1; cyclic AMP-responsive element-binding protein 1; CREB-1; transactivator protein; active transcription factor CREB; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CREB; MGC9284
• Gene ID: 1385
• mRNA Refseq: NM_004379
• Protein Refseq: NP_004370
• MIM: 123810
• UniProt ID: P16220