Recombinant Human CSF1 Protein (Glu33-Ser496), His tagged
Cat.No. : | CSF1-2521H |
Product Overview : | Recombinant human MCSF (Glu33-Ser496) protein fused with His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. M-CSF/CSF-1 is known to facilitate monocyte survival, monocyte-to-macrophage conversion, and macrophage proliferation. M-CSF/CSF-1 is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. It binds to the Colony stimulating factor 1 receptor. M-CSF/CSF-1 may also be involved in development of the placenta. The active form of M-CSF/CSF-1 is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF/CSF-1 induces cells of the monocyte/macrophage lineage. It also plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Upregulation of M-CSF/CSF-1 in the infarcted myocardium may have an active role in healing not only through its effects on cells of monocyte/macrophage lineage, but also by regulating endothelial cell chemokine expression. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 50.94 kDa |
Protein Length : | Glu33-Ser496 |
Purity : | >90 % as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | CSF1 colony stimulating factor 1 (macrophage) [ Homo sapiens (human) ] |
Official Symbol : | CSF1 |
Synonyms : | CSF1; colony stimulating factor 1 (macrophage); macrophage colony-stimulating factor 1; M CSF; MCSF; MGC31930; lanimostim; CSF-1; |
Gene ID : | 1435 |
mRNA Refseq : | NM_000757 |
Protein Refseq : | NP_000748 |
MIM : | 120420 |
UniProt ID : | P09603 |
Products Types
◆ Recombinant Protein | ||
Csf1-2159M | Recombinant Mouse Csf1 Protein, His-tagged | +Inquiry |
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CSF1-198H | Recombinant Human CSF1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
Csf1-1106M | Recombinant Mouse Csf1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CSF1-1934HCL | Recombinant Human CSF1 cell lysate | +Inquiry |
CSF1-001MCL | Recombinant Mouse CSF1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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