Recombinant Human CSF2 protein(Ala18-Glu144), hFc-tagged
Cat.No. : | CSF2-486H |
Product Overview : | Recombinant Human CSF2 (NP_000749.2) (Ala 18-Glu 144) was expressed in HEK293, fused with the Fc region of Human IgG1 at the N-terminus. |
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Source : | HEK293 |
Species : | Human |
Tag : | N-hFc |
Protein length : | Ala18-Glu144 |
Form : | Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | 1. Measured by its binding ability in a functional ELISA. Immobilized CD131 at 10 μg/ml (100 μl/well) can bind recombinant human GM-CSF / Fc with a linear range of 0.032-4 μg/ml. 2. Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 1-5 ng/mL. |
Molecular Mass : | The recombinant human GM-CSF/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 364 amino acids and has a predicted molecular mass of 41 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh GM-CSF/Fc monomer is approximately 48-55 kDa due to glycosylation. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 97 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | CSF2 colony stimulating factor 2 (granulocyte-macrophage) [ Homo sapiens ] |
Official Symbol : | CSF2 |
Synonyms : | CSF2; colony stimulating factor 2 (granulocyte-macrophage); granulocyte-macrophage colony-stimulating factor; GM CSF; GMCSF; granulocyte macrophage colony stimulating factor; molgramostin; sargramostim; CSF; colony-stimulating factor; granulocyte-macrophage colony stimulating factor; MGC131935; MGC138897; |
Gene ID : | 1437 |
mRNA Refseq : | NM_000758 |
Protein Refseq : | NP_000749 |
MIM : | 138960 |
UniProt ID : | P04141 |
Products Types
◆ Recombinant Protein | ||
CSF2-2539H | Recombinant Human CSF2 protein(18-144 aa), N-SUMO & C-His-tagged | +Inquiry |
Csf2-012C | Active Recombinant Rat Csf2 Protein (128 aa) | +Inquiry |
CSF2-48R | Active Recombinant Rat CSF2 Protein | +Inquiry |
CSF2-50P | Recombinant Active Pig CSF2 Protein, His-tagged(N-ter) | +Inquiry |
CSF2-43C | Active Recombinant Canine CSF2 Protein | +Inquiry |
◆ Lysates | ||
CSF2-1008MCL | Recombinant Mouse CSF2 cell lysate | +Inquiry |
CSF2-740RCL | Recombinant Rat CSF2 cell lysate | +Inquiry |
CSF2-3008HCL | Recombinant Human CSF2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionThe sequence of CSF2 is moderately conserved across different species.
The length of CSF2 protein varies but is typically around 144 amino acids.
The primary function of CSF2 is to regulate the production and differentiation of white blood cells.
CSF2 is often expressed in immune cells, specifically in macrophages, T cells, and endothelial cells.
CSF2 stands for Colony Stimulating Factor 2.
CSF2 dysregulation has been linked to autoimmune diseases and inflammatory disorders.
CSF2 is involved in the stimulation of stem cells to produce granulocytes and monocytes.
Customer Reviews (3)
Write a reviewThe product's adherence to regulatory standards aligned with our lab's commitment to responsible and transparent research.
The manufacturer's commitment to meeting regulatory requirements demonstrated its dedication to ethical research practices.
Compliance with industry standards minimized potential roadblocks in securing approvals for our experiments.
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