Recombinant Human CSF2, StrepII-tagged
Cat.No. : | CSF2-220H |
Product Overview : | Purified, full-length human recombinant Granulocyte-macrophage (GM-CSF) protein (amino acids 18-144, 127 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 14.5 kDa. (Accession NP_000749.2; UniProt P04141) |
- Specification
- Gene Information
- Related Products
Description : | GM-CSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. The GM-CSF gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. |
Source : | Human Cells |
Species : | Human |
Tag : | StrepII |
Form : | Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free). |
Protein length : | 18-144, 127 a.a. |
AA Sequence : | APARSPSPSTQPWEHVNAIQEARRL LNLSRDTAAEMNETVEVISEMFDLQ EPTCLQTRLELYKQGLRGSLTKLKG PLTMMASHYKQHCPPTPETSCATQI ITFESFKENLKDFLLVIPFDCWEPV QE |
Endotoxin : | <0.1 eu per ug protein by lal |
Purity : | >95% pure by SDS-PAGE |
Storage : | 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles. |
Reconstitution : | Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml. |
Gene Name : | CSF2 colony stimulating factor 2 (granulocyte-macrophage) [ Homo sapiens ] |
Official Symbol : | CSF2 |
Synonyms : | CSF2; colony stimulating factor 2 (granulocyte-macrophage); granulocyte-macrophage colony-stimulating factor; GM CSF; GMCSF; granulocyte macrophage colony stimulating factor; molgramostin; sargramostim; CSF; colony-stimulating factor; granulocyte-macrophage colony stimulating factor; MGC131935; MGC138897; |
Gene ID : | 1437 |
mRNA Refseq : | NM_000758 |
Protein Refseq : | NP_000749 |
MIM : | 138960 |
UniProt ID : | P04141 |
Chromosome Location : | 5q23-q31 |
Pathway : | Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Calcium signaling in the CD4+ TCR pathway, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
Function : | cytokine activity; granulocyte macrophage colony-stimulating factor receptor binding; growth factor activity; protein binding; |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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