Recombinant Human CTSB Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | CTSB-3874H |
Product Overview : | CTSB MS Standard C13 and N15-labeled recombinant protein (NP_680093) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. Multiple pseudogenes of this gene have been identified. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 37.8 kDa |
AA Sequence : | MWQLWASLCCLLVLANARSRPSFHP LSDELVNYVNKRNTTWQAGHNFYNV DMSYLKRLCGTFLGGPKPPQRVMFT EDLKLPASFDAREQWPQCPTIKEIR DQGSCGSCWAFGAVEAISDRICIHT NAHVSVEVSAEDLLTCCGSMCGDGC NGGYPAEAWNFWTRKGLVSGGLYES HVGCRPYSIPPCEHHVNGSRPPCTG EGDTPKCSKICEPGYSPTYKQDKHY GYNSYSVSNSEKDIMAEIYKNGPVE GAFSVYSDFLLYKSGVYQHVTGEMM GGHAIRILGWGVENGTPYWLVANSW NTDWGDNGFFKILRGQDHCGIESEV VAGIPRTDQYWEKITRTRPLEQKLI SEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | CTSB cathepsin B [ Homo sapiens (human) ] |
Official Symbol : | CTSB |
Synonyms : | CTSB; cathepsin B; cathepsin B1; APP secretase; cysteine protease; amyloid precursor protein secretase; APPS; CPSB; |
Gene ID : | 1508 |
mRNA Refseq : | NM_147783 |
Protein Refseq : | NP_680093 |
MIM : | 116810 |
UniProt ID : | P07858 |
Products Types
◆ Recombinant Protein | ||
CTSB-785H | Recombinant Human CTSB Protein, His-tagged | +Inquiry |
CTSB-3369H | Recombinant Human CTSB Protein, MYC/DDK-tagged | +Inquiry |
Ctsb-10530M | Recombinant Mouse Ctsb Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSB-2750H | Recombinant Human CTSB Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSB-2099H | Recombinant Human CTSB Protein, GST-tagged | +Inquiry |
◆ Native Protein | ||
CTSB-188B | Active Native Bovine Cathepsin B | +Inquiry |
CTSB-5328H | Native Human Cathepsin B | +Inquiry |
CTSB-26408TH | Native Human CTSB | +Inquiry |
◆ Lysates | ||
CTSB-3025HCL | Recombinant Human CTSB cell lysate | +Inquiry |
CTSB-1885MCL | Recombinant Mouse CTSB cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2366 | Cathepsin B (CTSB) Inhibitor Screening Kit (Fluorometric) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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